Evidence map›Paper›PMID 35392404›Full record

ArticleFrontiers in bioengineering and biotechnology2022

Biomechanical Properties of Mouse Carotid Arteries With Diet-Induced Metabolic Syndrome and Aging.

Anastasia Gkousioudi, Xunjie Yu, Jacopo Ferruzzi, Juncheng Qian, Richard D Wainford, Francesca Seta, Yanhang Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in bioengineering and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 12 citations in OpenAlex.

  1. Article
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  5. Sex differences in vascular aging and impact of GPER deletion.American journal of physiology. Heart and circulatory physiology · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Anastasia GkousioudiDepartment of Mechanical Engineering, Boston University, Boston, MA, United States.
Xunjie YuDepartment of Mechanical Engineering, Boston University, Boston, MA, United States.
Jacopo FerruzziDepartment of Bioengineering, The University of Texas at Dallas, Richardson, TX, United States.
Juncheng QianDepartment of Mechanical Engineering, Boston University, Boston, MA, United States.
Richard D WainfordDepartment of Pharmacology and Experimental Therapeutics, The Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA, United States.
Francesca SetaVascular Biology Section, The Whitaker Cardiovascular Institute, Boston University School of Medicine, Boston, MA, United States.
Yanhang ZhangDepartment of Mechanical Engineering, Boston University, Boston, MA, United States.
Boston University · USThe University of Texas at Dallas · US

Funding

Aging and hypertension: Integrated renal and sympathetic control of blood pressureR01AG062515 · NIA · EMORY UNIVERSITY · PI WAINFORD, RICHARD DAVID · 2019 to 2023
$3.5M
The role of Bcl11b in dementia associated with Parkinsons diseaseR01HL136311 · NHLBI · BOSTON UNIVERSITY MEDICAL CAMPUS · PI SETA, FRANCESCA · 2018 to 2022
$2.8M
Central mechanisms and novel biomarkers of the salt-sensitivity of blood pressureR01HL141406 · NHLBI · EMORY UNIVERSITY · PI WAINFORD, RICHARD DAVID · 2018 to 2021
$2.8M
Neural control of the kidney and long-term blood pressure regulationR01HL139867 · NHLBI · EMORY UNIVERSITY · PI WAINFORD, RICHARD DAVID · 2018 to 2021
$2.6M
NHLBI NIH HHS R01 HL136311NHLBI NIH HHS R01 HL139867NHLBI NIH HHS R01 HL141406NIA NIH HHS R01 AG062515
6 · The paper itself

Abstract

Metabolic syndrome increases the risk of cardiovascular diseases. Arteries gradually stiffen with aging; however, it can be worsened by the presence of conditions associated with metabolic syndrome. In this study, we investigated the combined effects of diet-induced metabolic syndrome and aging on the biomechanical properties of mouse common carotid arteries (CCA). Male mice at 2 months of age were fed a normal or a high fat and high sucrose (HFHS) diet for 2 (young group), 8 (adult group) and 18-20 (old group) months. CCAs were excised and subjected to

Indexed as

agingbiaxial inflation-extensionelastic energy storagematerial stiffnessmetabolic syndrome

Identifiers

PMID35392404
PMCPMC8980683
OpenAlexW4220891543

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.