Evidence map›Paper›PMID 35392398›Full record

ArticleHeliyon2022

Genetic predisposition of alopecia areata in jordanians: A case-control study.

Laith N Al-Eitan, Mansour A Alghamdi, Rawan O Al Momani, Hanan A Aljamal, Asim M Abdalla, Heitham M Mohammed

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Heliyon, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06545110 (Retinol Binding Protein 4 Expression and Its Genetic Variants in Severe Alopecia Areata Treated With Barcitinib.), which is not on this map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
2.0field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06545110 phase1active not recruitingnot on this mapstarted 2023, after this paper: background citation

Retinol Binding Protein 4 Expression and Its Genetic Variants in Severe Alopecia Areata Treated With Barcitinib.

TypeinterventionalSponsorSouth Valley UniversityRan2023 to 2024Enrolled120ConditionsAlopecia AreataArmsBaricitinib Oral Tablet
3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Alopecia areata.Nature reviews. Disease primers · 2025
    Review
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Laith N Al-EitanDepartment of Biotechnology and Genetic Engineering, Jordan University of Science and Technology, Irbid, 22110, Jordan.
Mansour A AlghamdiDepartment of Anatomy, College of Medicine, King Khalid University, Abha, 61421, Saudi Arabia.
Rawan O Al MomaniDepartment of Biotechnology and Genetic Engineering, Jordan University of Science and Technology, Irbid, 22110, Jordan.
Hanan A AljamalDepartment of Biotechnology and Genetic Engineering, Jordan University of Science and Technology, Irbid, 22110, Jordan.
Asim M AbdallaDepartment of Anatomy, College of Medicine, King Khalid University, Abha, 61421, Saudi Arabia.
Heitham M MohammedDepartment of Anatomy, College of Medicine, King Khalid University, Abha, 61421, Saudi Arabia.
Jordan University of Science and Technology · JOKing Khalid University · SA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Alopecia areata (AA) is a common non-scarring hair loss disease of defined patterns with varied patches size and body sites. The etiology of AA has a complex basis of autoimmunity, environment, and genetic variations. The latter factor is found to play a crucial role in AA risk. Thus, this study aimed to investigate the potential impact of specific immune-related gene polymorphisms among a cohort of Jordanian patients, which was previously reported in other populations. Blood samples of AA patients and control subjects were collected for genomic DNA (gDNA) extraction. Targeted single nucleotide polymorphisms (SNPs) of

Indexed as

Alopecia areataAutoimmunityGene polymorphismsGenetic markersHair folliclesTLR1

Identifiers

PMID35392398
PMCPMC8980757
OpenAlexW4220996158

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.