Evidence map›Paper›PMID 35392169›Full record

ArticleFrontiers in cell and developmental biology2022

Nicotinic Acid Adenine Dinucleotide Phosphate Induces Intracellular Ca

Pawan Faris, Claudio Casali, Sharon Negri, Lara Iengo, Marco Biggiogera, Angela Serena Maione, Francesco Moccia

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
2.1field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 14 citations in OpenAlex.

  1. CaBiomedicines · 2025
    Review
  2. Review
  3. Article
  4. Lysosomal TRPML1 triggers global CaFrontiers in physiology · 2024
    Article
  5. Store-Operated CaJournal of clinical medicine · 2023
    Review
  6. Review
  7. TRPML1-Induced Lysosomal CaInternational journal of molecular sciences · 2023
    Article
  8. Intracellular CaFrontiers in physiology · 2023
    Review
  9. GABACells · 2022
    Article
  10. Two-pore channels: going with the flows.Biochemical Society transactions · 2022
    Article
  11. Histamine activates an intracellular CaFrontiers in cell and developmental biology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Pawan FarisLaboratory of General Physiology, Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, Italy.
Claudio CasaliLaboratory of Cell Biology and Neurobiology, Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, Italy.
Sharon NegriLaboratory of General Physiology, Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, Italy.
Lara IengoVascular Biology and Regenerative Medicine Unit, Centro Cardiologico Monzino, IRCCS, Milan, Italy.
Marco BiggiogeraLaboratory of Cell Biology and Neurobiology, Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, Italy.
Angela Serena MaioneVascular Biology and Regenerative Medicine Unit, Centro Cardiologico Monzino, IRCCS, Milan, Italy.
Francesco MocciaLaboratory of General Physiology, Department of Biology and Biotechnology "Lazzaro Spallanzani", University of Pavia, Pavia, Italy.
University of Pavia · ITCentro Cardiologico Monzino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nicotinic acid adenine dinucleotide phosphate (NAADP) is a newly discovered second messenger that gates two pore channels 1 (TPC1) and 2 (TPC2) to elicit endo-lysosomal (EL) Ca

Indexed as

cardiac mesenchymal stem cellsmembrane contact sitesnicotinic acid adenine dinucleotide phosphate (NAADP)proliferationstore operated Ca2+ entrytwo-pore channels (TPCs)

Identifiers

PMID35392169
PMCPMC8980055
OpenAlexW4221041233

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.