Evidence map›Paper›PMID 35392114›Full record

ArticleFrontiers in veterinary science2022

Calf Diarrhea Is Associated With a Shift From Obligated to Facultative Anaerobes and Expansion of Lactate-Producing Bacteria.

Diego E Gomez, Lynna Li, Hanne Goetz, Jennifer MacNicol, Lisa Gamsjaeger, David L Renaud

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.

0numbers the graph read from it
0cells of the map it votes in
34citing papers in PubMed
7.9field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

34 citing papers in PubMed, 50 citations in OpenAlex.

  1. Article
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  6. Robust Goat-DerivedVeterinary sciences · 2026
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  16. Article
  17. Serum D-Lactate Concentrations in Dogs with Inflammatory Bowel Disease.Animals : an open access journal from MDPI · 2024
    Article
  18. Article
  19. Review
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Diego E GomezDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
Lynna LiDepartment of Clinical Studies, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
Hanne GoetzDepartment of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
Jennifer MacNicolDepartment of Animal Sciences, Ontario Agricultural College, University of Guelph, Guelph, ON, Canada.
Lisa GamsjaegerVetsuisse Faculty, Department for Farm Animals, Division of Ruminant Medicine, Zurich, Switzerland.
David L RenaudDepartment of Population Medicine, Ontario Veterinary College, University of Guelph, Guelph, ON, Canada.
University of Guelph · CACenter for Pediatric Endocrinology Zurich · CH

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Diarrhea is the leading cause of morbidity, mortality and antimicrobial drug use in calves during the first month of age. Alteration in the bacterial communities of the gastrointestinal tract occurs during diarrhea. Diarrheic calves often develop anion gap (AG) acidosis associated with increased concentrations of unmeasured anions including D- and L-lactate. However, studies investigating the association between gut microbiota alterations and the development of acid-base disorders in diarrheic calves are lacking. We investigated the fecal bacterial alterations of calves with diarrhea and its association with changes in blood pH, and AG. Blood and fecal samples from healthy and diarrheic veal calves were taken 7 days after arrival to the farm. The fecal microbiota of healthy and diarrheic calves was assessed by sequencing of 16S ribosomal RNA gene amplicons. Blood gas analysis was completed using an i-Stat analyzer. In healthy calves, higher richness, evenness, and diversity were observed compared to diarrheic calves.

Indexed as

acidemiaanion gap acidosisD-lactatedysbiosisL-lactate

Identifiers

PMID35392114
PMCPMC8981386
OpenAlexW4220926937

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.