Evidence map›Paper›PMID 35392072›Full record

ArticleFrontiers in immunology2022

Necroptosis Contributes to Persistent Inflammation During Acute Leptospirosis.

Suman Kundu, Advait Shetty, Maria Gomes-Solecki

Open access · goldAbstract read
In one paragraph

Article in Frontiers in immunology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.8field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Article
  3. TLR4 competence and mouse models of sublethal leptospirosis.PLoS neglected tropical diseases · 2025
    Article
  4. Article
  5. Article
  6. Exposure to live saprophyticbioRxiv : the preprint server for biology · 2024
    Article
  7. Article
  8. Article
  9. Frontiers in cellular and infection microbiology · 2024
    Article
  10. Article
  11. Intracellular behavior ofFrontiers in cellular and infection microbiology · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Hematogenous dissemination of pathogenic and non-pathogenicFrontiers in cellular and infection microbiology · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Suman KunduDepartment of Microbiology, Immunology and Biochemistry, The University of Tennessee Health Science Center, Memphis, TN, United States.
Advait ShettyDepartment of Pharmaceutical Sciences, The University of Tennessee Health Science Center, Memphis, TN, United States.
Maria Gomes-SoleckiDepartment of Microbiology, Immunology and Biochemistry, The University of Tennessee Health Science Center, Memphis, TN, United States.
University of Tennessee Health Science Center · US

Funding

Antibody isotyping for discrimination of disease stage and diagnosis of early Lyme disease.R43AI155211 · NIAID · IMMUNO TECHNOLOGIES, INC. · PI GOMES-SOLECKI, MARIA · 2020 to 2021
$594k
Low-cost Production of a Vaccine for Lyme Disease in MaizeR43AI152650 · NIAID · APPLIED BIOTECHNOLOGY INSTITUTE · PI EGELKROUT, ERIN, GOMES-SOLECKI, MARIA · 2021 to 2022
$594k
Role of TLR4 in persistent Leptospira infectionR21AI142129 · NIAID · UNIVERSITY OF TENNESSEE HEALTH SCI CTR · PI GOMES-SOLECKI, MARIA · 2019 to 2020
$418k
NIAID NIH HHS R21 AI142129NIAID NIH HHS R43 AI152650
6 · The paper itself

Abstract

Leptospirosis is an emerging infectious disease. Recently, canine and human leptospirosis outbreaks were reported in California and New York, respectively. In this study we evaluated the role that cell death processes play in the inflammatory response to

Indexed as

LeptospiraLeptospirosisAnimalsDogsInflammationMaleMiceMice, Inbred C3HNecroptosisApoptosisInflammationL. biflexaLeptospirosisL. interrogansMLKLNecroptosisRIP3

Identifiers

PMID35392072
PMCPMC8980737
OpenAlexW4221085488

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.