Evidence map›Paper›PMID 35392061›Full record

ArticleFrontiers in surgery2022

A Simple-To-Use Nomogram for Predicting Early Death in Metastatic Renal Cell Carcinoma: A Population-Based Study.

Tao Chen, Xiangpeng Zhan, Junfu Du, Xiaoqiang Liu, Wen Deng, Shuaishuai Zhao, Ming Jiang, Yunqiang Xiong, Xiaohai Zhang, Luyao Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Trial
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Tao ChenDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Xiangpeng ZhanDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Junfu DuDepartment of Urology, Wuning People's Hospital, Jiujiang, China.
Xiaoqiang LiuDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Wen DengDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Shuaishuai ZhaoDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Ming JiangDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Yunqiang XiongDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Xiaohai ZhangDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Luyao ChenDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Bin FuDepartment of Urology, The First Affiliated Hospital of Nanchang University, Nanchang, China.
Nanchang University · CNFirst Affiliated Hospital of Nanchang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Metastatic renal cell carcinoma (mRCC) is usually considered to have a poor prognosis, which has a high risk of early death (≤3 months). Our aim was to developed a predictive nomogram for early death of mRCC. Methods: The SEER database was accessed to obtain the related information of 6,005 mRCC patients between 2010 and 2015. They were randomly divided into primary cohort and validation cohort in radio of 7:3. The optimal cut-off point regarding age at diagnosis and tumor size were identified by the X-tile analysis. Univariate and multivariate logistic regression models were applied to determine significant independent risk factors contributed to early death. A practical nomogram was constructed and then verified by using calibration plots, receiver operating characteristics (ROCs) curve, and decision curve analysis (DCA). Results: There were 6,005 patients with mRCC included in the predictive model, where 1,816 patients went through early death (death within ≤3 months of diagnosis), and among them 1,687 patients died of mRCC. Based on 11 significant risk factors, including age, grade, Conclusions: The nomogram may play a major part in distinguishing the early death of mRCC patients, which can assist clinicians in individualized medicine.

Indexed as

early deathnomogramsprognosisrenal cell carcinomaSEER database

Identifiers

PMID35392061
PMCPMC8980350
OpenAlexW4221076685

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.