Evidence map›Paper›PMID 35392005›Full record

ArticleNagoya journal of medical science2022

Progression of liver fibrosis and associated factors among chronic hepatitis B patients at a general hospital in Northern Vietnam.

Ngoc Minh Luu, Thi Kim Thuy Nguyen, Thu Trang Vu, Thai Son Dinh, Ngoc Hoat Luu, Thi Thanh Toan Do, Van Son Nguyen, Thi Bich Van Ha, Dinh Chuc Nguyen, Thi Huong Tran and 7 more

Abstract read
In one paragraph

Article in Nagoya journal of medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

17 authors.

Ngoc Minh LuuInstitute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.
Thi Kim Thuy NguyenPhu Tho Provincial General Hospital, Phu Tho, Vietnam.
Thu Trang VuInstitute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.
Thai Son DinhInstitute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.
Ngoc Hoat LuuMedical Faculty, Phenikaa University, Hanoi, Vietnam.
Thi Thanh Toan DoInstitute for Preventive Medicine and Public Health, Hanoi Medical University, Hanoi, Vietnam.
Van Son NguyenPhu Tho Provincial General Hospital, Phu Tho, Vietnam.
Thi Bich Van HaPhu Tho Provincial General Hospital, Phu Tho, Vietnam.
Dinh Chuc NguyenPhu Tho Provincial General Hospital, Phu Tho, Vietnam.
Thi Huong TranPhu Tho Provincial General Hospital, Phu Tho, Vietnam.
Thi Thuy Hang PhungPhu Tho Provincial General Hospital, Phu Tho, Vietnam.
Xuan Phuong DuongPhu Tho Provincial General Hospital, Phu Tho, Vietnam.
Quynh Long KhuongCenter for Population Health Sciences, Hanoi University of Public Health, Hanoi, Vietnam.
Thi Thu Trang NguyenDivision of Public Health and Nutrition, General Department of Preventive Medicine, Ministry of Health, Hanoi, Vietnam.
Yu Mon SawGraduate School of Medicine, Nagoya University, Nagoya, Japan.
Thi Ngoc Anh HoangDepartment of Epidemiology, National Institute of Hygiene and Epidemiology, Hanoi, Vietnam.
Thi Nhan NguyenForeign Language Department, Hanoi Medical University, Hanoi, Vietnam.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Evaluation of liver fibrosis is necessary to make the therapeutic decision and assess the prognosis of CHB patients. The current study aimed to describe the progression and identify some influencing factors in patients with chronic hepatitis B at a General Hospital in Northern Vietnam. The longitudinal study included 55 eligible subjects diagnosed Hepatitis-B-virus. Dependent variable was the aspartate aminotransferase/platelet ratio index and we collected some demographic variables and disease related and behaviour variables. Bayesian Model Averaging was used to select variables into model. Mixed-effect linear models were used to evaluate the change of the aspartate aminotransferase/platelet ratio index over time and identify related factors. the aspartate aminotransferase/platelet ratio index differences between examinations, age of participants, working status were statistically significant. This pattern indicated that the average the aspartate aminotransferase/platelet ratio index of the population decreased by 0.005 (95% CI=-0.009; -0.001) after each patient's visit, and increased by 0.013 if the patient's age increased by 1 year (95% CI=0.005; 0.0219). For non-working patients, the aspartate aminotransferase/platelet ratio index was lower, coefficient was -0.054 (95% CI=-0.108; 0.001). Other variables such as gender, education level, time for disease detection, drinking tea, alcohol consumption, forgetting to take medicine and the aspartate aminotransferase/platelet ratio index were not significantly different. The study showed that the majority of study subjects had average the aspartate aminotransferase/platelet ratio index, and were relatively well controlled and treated during the study. Age and working status are factors that influence the the aspartate aminotransferase/platelet ratio index.

Indexed as

Hepatitis B, ChronicAspartate AminotransferasesBayes TheoremBiomarkersHospitals, GeneralHumansLiver CirrhosisLongitudinal StudiesPlatelet CountRetrospective StudiesSeverity of Illness IndexVietnamAspartate AminotransferasesBiomarkersAPRI indexassociated factorshepatitis B virus infectionliver fibrosismixed-effect model

Identifiers

PMID35392005
PMCPMC8971045

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.