Evidence map›Paper›PMID 35391883›Full record

ArticleFrontiers in medicine2022

Reduced FEV

Yi-Luen Shen, Chia-I Shen, Chi-Lu Chiang, Hsu-Ching Huang, Kun-Ta Chou, Chao-Hua Chiu, Yuh-Min Chen, Yung-Hung Luo

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Article
  6. Observational
  7. Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Yi-Luen ShenDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Chia-I ShenDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Chi-Lu ChiangDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Hsu-Ching HuangDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Kun-Ta ChouDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Chao-Hua ChiuDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Yuh-Min ChenDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
Yung-Hung LuoDepartment of Chest Medicine, Taipei Veterans General Hospital, Taipei, Taiwan.
National Yang Ming Chiao Tung University · TWTaipei Veterans General Hospital · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The aim of study is to investigate the influence of pulmonary function on the prognosis in patients with advanced non-small cell lung cancer (NSCLC) receiving immune checkpoint inhibitors (ICI). Patients and Methods: Data were collected retrospectively from 151 patients with stage IV NSCLC who received ICI and completed spirometry before ICI therapy in Taipei Veterans General Hospital between January 2016 and December 2020. The co-primary end points were overall survival (OS) and progression-free survival (PFS) between groups divided by 80% predicted FEV Results: Among 151 patients enrolled to this study, 67.5% of patients were men, 75.5% were adenocarcinoma, 24.5% had known targetable driver mutation, 33.8% received first-line ICI, and 62.8% received ICI monotherapy. The objective response rate was 24.5% and disease control rate was 54.3%. In multivariable analysis, patient with reduced FEV Conclusions: Reduced FEV

Indexed as

advanced non-small cell lung cancerchronic lung disease (CLD)forced expiratory volume (FEV) 1 secondimmune checkpoint inhibitor (ICI)pulmonary function test (PFT)

Identifiers

PMID35391883
PMCPMC8980716
OpenAlexW4220829881

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.