Evidence map›Paper›PMID 35391847›Full record

ArticleFrontiers in cardiovascular medicine2022

A Deep Learning System for Fully Automated Retinal Vessel Measurement in High Throughput Image Analysis.

Danli Shi, Zhihong Lin, Wei Wang, Zachary Tan, Xianwen Shang, Xueli Zhang, Wei Meng, Zongyuan Ge, Mingguang He

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
37citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

37 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Danli ShiState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Zhihong LinFaculty of Engineering, Monash University, Melbourne, VIC, Australia.
Wei WangState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.
Zachary TanCentre for Eye Research Australia, East Melbourne, VIC, Australia.
Xianwen ShangDepartment of Ophthalmology, Guangdong Provincial People's Hospital, Guangdong Eye Institute, Guangdong Academy of Medical Sciences, Guangzhou, China.
Xueli ZhangDepartment of Ophthalmology, Guangdong Provincial People's Hospital, Guangdong Eye Institute, Guangdong Academy of Medical Sciences, Guangzhou, China.
Wei MengGuangzhou Vision Tech Medical Technology Co., Ltd., Guangzhou, China.
Zongyuan GeResearch Center and Faculty of Engineering, Monash University, Melbourne, VIC, Australia.
Mingguang HeState Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-sen University, Guangzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Motivation: Retinal microvasculature is a unique window for predicting and monitoring major cardiovascular diseases, but high throughput tools based on deep learning for in-detail retinal vessel analysis are lacking. As such, we aim to develop and validate an artificial intelligence system (Retina-based Microvascular Health Assessment System, RMHAS) for fully automated vessel segmentation and quantification of the retinal microvasculature. Results: RMHAS achieved good segmentation accuracy across datasets with diverse eye conditions and image resolutions, having AUCs of 0.91, 0.88, 0.95, 0.93, 0.97, 0.95, 0.94 for artery segmentation and 0.92, 0.90, 0.96, 0.95, 0.97, 0.95, 0.96 for vein segmentation on the AV-WIDE, AVRDB, HRF, IOSTAR, LES-AV, RITE, and our internal datasets. Agreement and repeatability analysis supported the robustness of the algorithm. For vessel analysis in quantity, less than 2 s were needed to complete all required analysis.

Indexed as

artificial intelligenceautomated analysiscardiovascular diseaseepidemiologyhierarchical vessel morphology

Identifiers

PMID35391847
PMCPMC8980780

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.