Evidence map›Paper›PMID 35391660›Full record

Observational studyEuropean geriatric medicine2022

Surgical-site infection after hip fracture surgery: preoperative full-body disinfection compared to local disinfection of the surgical site-a population-based observational cohort study.

Noelle Probert, Åsa G Andersson, Anders Magnuson, Elin Kjellberg, Per Wretenberg

Erratum issuedOpen access · hybridAbstract readObservational Study
In one paragraph

Observational study in European geriatric medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.4field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 1 country.

Noelle ProbertFaculty of Medicine and Health, Örebro University, Örebro, Sweden. noelle.probert@oru.se.ORCID 0000-0002-7406-5304
Åsa G AnderssonFaculty of Medicine and Health, Örebro University, Örebro, Sweden.
Anders MagnusonClinical Epidemiology and Biostatistics, School of Medical Sciences, Örebro University, Örebro, Sweden.
Elin KjellbergDepartment of Infectious Diseases, Central Hospital of Kristianstad, Kristianstad, Sweden.
Per WretenbergFaculty of Medicine and Health, Örebro University, Örebro, Sweden.
Örebro University · SEKristianstad University · SE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSwedish national guidelines recommend full-body disinfection (FBD) with 4% chlorhexidine before hip fracture surgery to prevent surgical-site infection (SSI) despite little evidence. Our objective was to compare preoperative FBD with local disinfection (LD) of the surgical site regarding SSI incidence.

methodsAll patients with hip fracture, operated at a hospital in Sweden, January 1, 2018 to December 31, 2019 were included. Patients in 2018 (n = 237) were prepared with FBD and patients in 2019 (n = 259) with LD. Primary outcome was SSI and secondary outcome was SSI and/or death. We adjusted for potential confounders with logistic regression. The adjusted analysis was performed in two models to enable assessment of variables that lacked either outcome; in the first model, these variables were not adjusted, and the second model was restricted to a sub-population not affected by respective variables.

resultsThere were 16 (6.8%) cases of SSI in 2018 and 8 (3.1%) cases in 2019. FBD (2018) compared to LD (2019) presented an adjusted OR of 1.9 (95%CI 0.8-4.9, P = 0.16) respectively 2.0 (95%CI 0.8-5.1, P = 0.14) in the two models of the logistic regression. In addition, 40 (16.9%) patients in 2018 and 29 (11.2%) patients in 2019 had the combined outcome of SSI and/or death, adjusted OR 1.6 (95% CI 0.9-2.8, P = 0.08) respectively 1.7 (95% CI 0.9-2.9, P = 0.06).

conclusionWe found a non-significant increased risk of SSI 2018 compared to 2019 after adjustment. Randomized control trials are needed. Nonetheless, results suggest that LD is not inferior to FBD regarding SSI prevention, meaning patients could potentially be spared substantial pain.

Indexed as

ChlorhexidineHip FracturesCohort StudiesDisinfectionHumansSurgical Wound InfectionChlorhexidineDisinfectionHip fractureHip fracture surgerySurgical-site infection

Identifiers

PMID35391660
PMCPMC9553784
OpenAlexW4225589984

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.