Evidence map›Paper›PMID 35391634›Full record

ArticleEuropean journal of applied physiology2022

A breathing mask attenuates acute airway responses to exercise in sub-zero environment in healthy subjects.

Nikolai Stenfors, Hampus Persson, Alasdair Tutt, Ellen Tufvesson, Erik P Andersson, Mats Ainegren, Helen G Hanstock

Open access · hybridAbstract read
In one paragraph

Article in European journal of applied physiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.3field-weighted citation impact, top 42% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Trial
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Nikolai StenforsUnit of Medicine, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden. nikolai.stenfors@umu.se.ORCID http://orcid.org/0000-0002-1684-1301
Hampus PerssonUnit of Medicine, Department of Public Health and Clinical Medicine, Umeå University, Umeå, Sweden.
Alasdair TuttSwedish Winter Sports Research Centre, Department of Health Sciences, Mid Sweden University, Östersund, Sweden.
Ellen TufvessonDepartment of Clinical Sciences Lund, Respiratory Medicine and Allergology, Lund University, Lund, Sweden.
Erik P AnderssonSwedish Winter Sports Research Centre, Department of Health Sciences, Mid Sweden University, Östersund, Sweden.
Mats AinegrenSports Tech Research Centre, Department of Quality Management and Mechanical Engineering, Mid Sweden University, Östersund, Sweden.
Helen G HanstockSwedish Winter Sports Research Centre, Department of Health Sciences, Mid Sweden University, Östersund, Sweden.
Mid Sweden University · SEUmeå University · SELund University · SE

Funding

Gunhild och Assar Karlssons donationsfond 2019HeartLungFoundation 20190261Region Jämtland Härjedalen JLL-931753
6 · The paper itself

Abstract

purposeCold air exposure is associated with increased respiratory morbidity and mortality. Repeated inhalation of cold and dry air is considered the cause of the high prevalence of asthma among winter endurance athletes. This study assessed whether a heat- and moisture-exchanging breathing device (HME) attenuates airway responses to high-intensity exercise in sub-zero temperatures among healthy subjects.

methodsUsing a randomized cross-over design, 23 healthy trained participants performed a 30-min warm-up followed by a 4-min maximal, self-paced running time trial in - 15 °C, with and without HME. Lung function was assessed pre- and immediately post-trials. Club cell protein (CC-16), 8-isoprostane, and cytokine concentrations were measured in plasma and urine pre- and 60 min post trials. Symptoms were assessed prior to, during, and immediately after each trial in the chamber.

resultsHME use attenuated the decrease in forced expiratory volume in 1 s (FEV

conclusionThe HME attenuated acute airway responses induced by moderate-to-maximal-intensity exercise in - 15 °C in healthy subjects. Further studies are needed to examine whether this HMEs could constitute primary prevention against asthma in winter endurance athletes.

Indexed as

AsthmaExerciseCross-Over StudiesCytokinesForced Expiratory VolumeHealthy VolunteersHumansRespirationCytokinesAirway epithelial damageCold temperatureExercise-induced bronchoconstrictionHeat- and moisture-exchanging breathing device

Identifiers

PMID35391634
PMCPMC9132816
OpenAlexW4226027571

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.