Evidence map›Paper›PMID 35391571›Full record

ArticleMikrochimica acta2022

Microneedle-based nanoporous gold electrochemical sensor for real-time catecholamine detection.

Cristina Tortolini, Anthony E G Cass, Riccardo Pofi, Andrea Lenzi, Riccarda Antiochia

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Mikrochimica acta, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
4.3field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 53 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 2 institutions in 2 countries.

Cristina TortoliniDepartment of Chemistry and Drug Technologies, Sapienza University of Rome, P.le Aldo Moro 5, 00185, Rome, Italy.
Anthony E G CassDepartment of Chemistry & Institute of Biomedical Engineering, Imperial College, London, UK.
Riccardo PofiDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Andrea LenziDepartment of Experimental Medicine, Sapienza University of Rome, Rome, Italy.
Riccarda AntiochiaDepartment of Chemistry and Drug Technologies, Sapienza University of Rome, P.le Aldo Moro 5, 00185, Rome, Italy. riccarda.antiochia@uniroma1.it.ORCID http://orcid.org/0000-0001-8990-8506
Sapienza University of Rome · ITNIHR Imperial Biomedical Research Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dopamine (DA), epinephrine (EP), and norepinephrine (NEP) are the main catecholamine of clinical interest, as they play crucial roles in the regulation of nervous and cardiovascular systems and are involved in some brain behaviors, such as stress, panic, anxiety, and depression. Therefore, there is an urgent need for a reliable sensing device able to provide their continuous monitoring in a minimally invasive manner. In this work, the first highly nanoporous gold (h-nPG) microneedle-based sensor is presented for continuous monitoring of catecholamine in interstitial fluid (ISF). The h-nPG microneedle-based gold electrode was prepared by a simple electrochemical self-templating method that involves two steps, gold electrodeposition and hydrogen bubbling at the electrode surface, realized by sweeping the potential between + 0.8 V and 0 V vs Ag/AgCl for 25 scans in a 10 mM HAuCl

Indexed as

GoldNanoporesCatecholaminesElectrodesNeedlesCatecholaminesGoldCatecholamineDopamineElectrochemical sensorEpinephrineMicroneedlesNanoporous gold needleNorepinephrine

Identifiers

PMID35391571
PMCPMC8989844
OpenAlexW4223521431

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.