Evidence map›Paper›PMID 35391494›Full record

ArticleBioelectromagnetics2022

Electromagnetic Fields Generated by the IteraCoil Device Differentiate Mesenchymal Stem Progenitor Cells Into the Osteogenic Lineage.

Gagik Greg Haroutunian, Ashot Tsaghikian, Elena Fedorova, Pratima Chaurasia, Gabriele Luca Gusella, Arevik Mosoian

Open access · greenAbstract read
In one paragraph

Article in Bioelectromagnetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 53% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 1 country.

Gagik Greg HaroutunianKeck School of Medicine, USC, Children's Hospital Los Angeles, Los Angeles, California.
Ashot TsaghikianData Processing and Field Engineering Corp., Glendale, California.
Elena FedorovaSkinAxis LLC, Cedar Knolls, New Jersey.
Pratima ChaurasiaIcahn School of Medicine at Mount Sinai, New York, New York.
Gabriele Luca GusellaSkinAxis LLC, Cedar Knolls, New Jersey.
Arevik MosoianSkinAxis LLC, Cedar Knolls, New Jersey.ORCID http://orcid.org/0000-0003-0700-5210
Thomas Cole Historic House · USChildren's Hospital of Los Angeles · USGlendale Community College · USIcahn School of Medicine at Mount Sinai · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rapid advances in mesenchymal stem progenitor cells (MSPCs) have rendered impetus into the area of cell therapy and regenerative medicine. The main promise of future stem cell therapies is their reliance on autologous stem cells derived from adipose tissue, which also includes treatments of bone fractures and degeneration. The effectiveness of different electric devices utilized to reprogram MSPCs toward osteogenic differentiation has provided varying degrees of effectiveness for clinical use. Adipose tissue-derived MSPCs were flow-cytometrically characterized and further differentiated into osteoblasts by culturing either in growth medium with pro-osteogenic supplements or without supplements with alternating electromagnetic field (EMF) generated by IteraCoil. IteraCoil is a multi-solenoid coil with a specific complex geometry that creates a 3D-EMF with desired parameters without directly applying electrodes to the cells and tissues. The flow-cytometric analysis of highly enriched (≥95%) adipose-derived MSPCs (CD34

Indexed as

Mesenchymal Stem CellsOsteogenesisCell DifferentiationCells, CulturedElectromagnetic FieldsHumansOsteoblastsalternating current (AC)alternating electromagnetic field (EMF)chondrogenic differentiationmesenchymal stem progenitor cells (MSPCs)osteogenic differentiation

Identifiers

PMID35391494
PMCPMC9325380
OpenAlexW4224235610

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.