Evidence map›Paper›PMID 35390486›Full record

ArticleJournal of the American College of Cardiology2022

Trends in Clinical Presentation, Management, and Outcomes of STEMI in Patients With COVID-19.

Santiago Garcia, Payam Dehghani, Larissa Stanberry, Cindy Grines, Rajan A G Patel, Keshav R Nayak, Avneet Singh, Wah Wah Htun, Ameer Kabour, Nima Ghasemzadeh and 17 more

Open access · greenAbstract readMulticenter Study
In one paragraph

Article in Journal of the American College of Cardiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
2.5field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 26 citations in OpenAlex.

  1. Persistent One-Year Mortality Gradient After STEMI and COVID-19: Long-Term Outcomes From the NACMI Registry.Journal of the Society for Cardiovascular Angiography & Interventions · 2026
    Article
  2. Article
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  7. Primary PCI, Thrombus, and COVID-19: Remembrance of Things Past.Journal of the American College of Cardiology · 2023
    Article
  8. Observational
  9. Comparative Analysis of Patients With STEMI and COVID-19 Between Canada and the United States.Journal of the Society for Cardiovascular Angiography & Interventions · 2023
    Article
  10. The impact of the coronavirus pandemic on patients hospitalized due to acute coronary syndrome.Postepy w kardiologii interwencyjnej = Advances in interventional cardiology · 2023
    Review
  11. Review
  12. Review
  13. Review
  14. Article
  15. [Acute coronary syndromes and COVID-19: An informative imbalance].Archives des maladies du coeur et des vaisseaux. Pratique · 2022
    Review
  16. Updates on the Management of STEMI in 2021: Beyond COVID-19.Journal of the American College of Cardiology · 2022
    Article
  17. Review
  18. STEMIs and a Closer Look at MINOCA During the COVID-19 Pandemic.Journal of the Society for Cardiovascular Angiography & Interventions
    Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

27 authors at 19 institutions in 2 countries.

Santiago GarciaMinneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA; The Carl and Edyth Lindner Center for Research and Education, The Christ Hospital, Cincinnati, Ohio, USA. Electronic address: santiagogarcia@me.com.
Payam DehghaniPrairie Vascular Research Inc, Regina, Saskatchewan, Canada.
Larissa StanberryMinneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA.
Cindy GrinesNorthside Cardiovascular Institute, Atlanta, Georgia, USA; Society for Cardiovascular Angiography and Interventions (SCAI), Washington, DC, USA.
Rajan A G PatelOchsner Medical Center, New Orleans, Louisiana, USA.
Keshav R NayakDepartment of Cardiology Scripps Mercy Hospital, San Diego, California, USA.
Avneet SinghNorth Shore University Hospital and Long Island Jewish Medical Center (NS/LIJ), Zucker School of Medicine at Hofstra, Queens, New York, USA.
Wah Wah HtunGundersen Health System, La Crosse, Wisconsin, USA.
Ameer KabourMercy St. Vincent's Medical Center, Toledo, Ohio, USA.
Nima GhasemzadehGeorgia Heart Institute, Northeast Georgia Medical Center, Gainesville, Georgia, USA.
Cristina SaninaMontefiore Medical Center and Albert Einstein College of Medicine, New York, New York, USA.
Joseph AragonSanta Barbara Cottage Hospital, Santa Barbara, California, USA.
M Chadi AlraiesDetroit Medical Center, Detroit, Michigan, USA.
Catherine BenzigerEssentia Health, Duluth, Minnesota, USA.
Brynn OkesonMinneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA.
Ross GarberichMinneapolis Heart Institute Foundation, Minneapolis, Minnesota, USA.
Frederick G WeltAmerican College of Cardiology Interventional Cardiology Section Leadership Council, Washington, DC, USA; University of Utah Health Sciences, Salt Lake City, Utah, USA.
Laura DavidsonNorthwestern University, Feinberg School of Medicine, Chicago, Illinois, USA.
Abdul Moiz HafizSouthern Illinois University School of Medicine, Springfield, Illinois, USA.
Deepak AcharyaUniversity of Arizona Sarver Heart Center, Tucson, Arizona, USA.
Jay StoneCommunity Medical Center (RWJ Barnabas Health), Toms River, New Jersey, USA.
Aditya MehraJersey Shore University Medical Center, Hackensack Meridian Health, Neptune, New Jersey, USA.
Shy AmlaniWilliam Osler Health System-Brampton, Brampton, Ontario, Canada.
Ehtisham MahmudUniversity of California, San Diego, Sulpizio Cardiovascular Center, La Jolla, California, USA.
Jay GiriUniversity of Pennsylvania, Philadelphia, Pennsylvania, USA. Electronic address: https://twitter.com/jaygirimd.
Mehmet YildizThe Carl and Edyth Lindner Center for Research and Education, The Christ Hospital, Cincinnati, Ohio, USA.
Timothy D HenryThe Carl and Edyth Lindner Center for Research and Education, The Christ Hospital, Cincinnati, Ohio, USA. Electronic address: https://twitter.com/HenrytTimothy.
Minneapolis Heart Institute Foundation · USChrist Hospital · USDetroit Medical Center · USEssentia Health · USGenome Prairie · CAGundersen Health System · USLong Island Jewish Medical Center · USMontefiore Medical Center · USNortheast Georgia Medical Center · USNorthside Hospital · USNorthwestern University · USOchsner Medical Center · USSanta Barbara Cottage Hospital · USScripps Mercy Hospital · USSouthern Illinois University School of Medicine · USSt. Vincent's Medical Center · USUniversity of Arizona · USUniversity of California, San Diego · USUniversity of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe previously reported high in-hospital mortality for ST-segment elevation myocardial infarction (STEMI) patients with COVID-19 treated in the early phase of the pandemic.

objectivesThe purpose of this study was to describe trends of COVID-19 patients with STEMI during the course of the pandemic.

methodsThe NACMI (North American COVID-19 STEMI) registry is a prospective, investigator-initiated, multicenter, observational registry of hospitalized STEMI patients with confirmed or suspected COVID-19 infection in North America. We compared trends in clinical characteristics, management, and outcomes of patients treated in the first year of the pandemic (January 2020 to December 2020) vs those treated in the second year (January 2021 to December 2021).

resultsA total of 586 COVID-19-positive patients with STEMI were included in the present analysis; 227 treated in Y2020 and 359 treated in Y2021. Patients' characteristics changed over time. Relative to Y2020, the proportion of Caucasian patients was higher (58% vs 39%; P < 0.001), patients presented more frequently with typical ischemic symptoms (59% vs 51%; P = 0.04), and patients were less likely to have shock pre-PCI (13% vs 18%; P = 0.07) or pulmonary manifestations (33% vs. 47%; P = 0.001) in Y2021. In-hospital mortality decreased from 33% (Y2020) to 23% (Y2021) (P = 0.008). In Y2021, none of the 22 vaccinated patients expired in hospital, whereas in-hospital death was recorded in 37 (22%) unvaccinated patients (P = 0.009).

conclusionsSignificant changes have occurred in the clinical characteristics and outcomes of STEMI patients with COVID-19 infection during the course of the pandemic.

Indexed as

COVID-19Percutaneous Coronary InterventionST Elevation Myocardial InfarctionHospital MortalityHumansProspective StudiesCOVID-19heart attackoutcomesSTEMI

Identifiers

PMID35390486
PMCPMC8978699
OpenAlexW4223576907

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.