Evidence map›Paper›PMID 35390063›Full record

ArticlePloS one2022

Cues to improve antibiotic-allergy registration: A mixed-method study.

Martijn Sijbom, Karolina K Braun, Frederike L Büchner, Leti van Bodegom-Vos, Bart J C Hendriks, Mark G J de Boer, Mattijs E Numans, Merel M C Lambregts

Erratum issuedOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.9field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Martijn SijbomDepartment of Public Health and Primary Care Campus-Den Haag, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-7264-269X
Karolina K BraunDepartment of Public Health and Primary Care Campus-Den Haag, Leiden University Medical Center, Leiden, The Netherlands.
Frederike L BüchnerDepartment of Public Health and Primary Care Campus-Den Haag, Leiden University Medical Center, Leiden, The Netherlands.
Leti van Bodegom-VosDepartment of Biomedical Data Sciences, Leiden University Medical Center, Leiden, The Netherlands.
Bart J C HendriksDepartment of Clinical Pharmacy and Toxicology, Leiden University Medical Center, Leiden, The Netherlands.
Mark G J de BoerDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Mattijs E NumansDepartment of Public Health and Primary Care Campus-Den Haag, Leiden University Medical Center, Leiden, The Netherlands.ORCID 0000-0002-0368-5426
Merel M C LambregtsDepartment of Infectious Diseases, Leiden University Medical Center, Leiden, The Netherlands.
Leiden University Medical Center · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundApproximately 2% of patients in primary care practice and up to 25% of hospital patients are registered as being allergic to an antibiotic. However, up to 90% of these registrations are incorrect, leading to unnecessary prescription of 2nd choice antibiotics with the attendant loss of efficacy, increased toxicity and antibiotic resistance. To improve registration, a better understanding is needed of how incorrect labels are attributed.

objectiveTo investigate the quality of antibiotic allergy registration in primary care and identify determinants to improve registration of antibiotic allergies.

designRegistration of antibiotic allergies in primary care practices were analysed for 1) completeness and 2) correctness. To identify determinants for improvement, semi-structured interviews with healthcare providers from four healthcare domains were conducted.

participantsA total of 300 antibiotic allergy registrations were analysed for completeness and correctness. Thirty-four healthcare providers were interviewed. MAIN MEASURES: A registration was defined as complete when it included a description of all symptoms, time to onset of symptoms and the duration of symptoms. It was defined as correct when the conclusion was concordant with the Salden criteria. Determinants of correct antibiotic allergy registrations were divided into facilitators or obstructers. KEY

resultsRates of completeness and correctness of registrations were 0% and 29.3%, respectively. The main perceived barriers for correct antibiotic allergy registration were insufficient knowledge, lack of priority, limitations of registration features in electronic medical records (EMR), fear of medical liability and patients interpreting side-effects as allergies.

conclusionsThe quality of antibiotic allergy registrations can be improved. Potential interventions include raising awareness of the consequences of incomplete and the importance of correct registrations, by continued education, and above all simplifying registration in an EMR by adequate ICT support.

Indexed as

CuesDrug HypersensitivityAnti-Bacterial AgentsDrug Resistance, MicrobialElectronic Health RecordsHumansAnti-Bacterial Agents

Identifiers

PMID35390063
PMCPMC8989191
OpenAlexW4226210015

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.