Evidence map›Paper›PMID 35390043›Full record

ArticlePloS one2022

Changes in alcohol use and mood during the COVID-19 pandemic among individuals with traumatic brain injury: A difference-in-difference study.

Raj G Kumar, Dmitry Esterov, Rachel Sayko Adams, John D Corrigan, Shannon B Juengst, Nancy D Chiaravalloti, Belinda Yew, Laura E Dreer, Kristen Dams-O'Connor

Open access · goldAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
1.3field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Which risk factors significantly influence the outcome of traumatic brain injured patients with alcohol use disorder?European journal of trauma and emergency surgery : official publication of the European Trauma Society · 2024
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 7 institutions in 1 country.

Raj G KumarDepartment of Rehabilitation & Human Performance, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.ORCID 0000-0002-0858-3533
Dmitry EsterovDepartment of Physical Medicine and Rehabilitation, Mayo Clinic, Rochester, MN, United States of America.
Rachel Sayko AdamsInstitute for Behavioral Health, The Heller School for Social Policy and Management, Brandeis University, Waltham, Massachusetts, United States of America.ORCID 0000-0003-4450-0712
John D CorriganDepartment of Physical Medicine and Rehabilitation, The Ohio State University, Columbus, OH, United States of America.ORCID 0000-0002-7591-5622
Shannon B JuengstTIRR Memorial Hermann, Houston TX, United States of America.
Nancy D ChiaravallotiKessler Foundation, East Hanover, NJ, United States of America.
Belinda YewDepartment of Rehabilitation & Human Performance, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Laura E DreerDepartment of Ophthalmology & Visual Sciences, University of Alabama at Birmingham, Birmingham, AL, United States of America.
Kristen Dams-O'ConnorDepartment of Rehabilitation & Human Performance, Icahn School of Medicine at Mount Sinai, New York, NY, United States of America.
Icahn School of Medicine at Mount Sinai · USMayo Clinic in Florida · USMemorial Hermann Institute for Rehabilitation and Research Foundation · USMental Illness Research, Education and Clinical Centers · USRutgers, The State University of New Jersey · USThe Ohio State University · USUniversity of Alabama at Birmingham · US

Funding

Visual Phenotyping CoreP30EY003039 · NEI · UNIVERSITY OF ALABAMA AT BIRMINGHAM · PI Paul Douglas Gamlin · 1985 to 2026
$16.9M
The Late Effects of TBI (LETBI) Study: Injury Patterns and Biological Markers of Post-Traumatic NeurodegenerationRF1NS115268 · NINDS · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI Kristen Dams-O'Connor · 2019 to 2026
$10.3M
Leveraging existing data resources to characterize health and clinical care among older adults with traumatic brain injuryK99HD106060 · NICHD · ICAHN SCHOOL OF MEDICINE AT MOUNT SINAI · PI KUMAR, RAJ GOPALAN · 2021 to 2022
$260k
ACL HHS 90DP0038ACL HHS 90DPTB0001ACL HHS 90DPTB0003ACL HHS 90DPTB0009ACL HHS 90DPTB0012ACL HHS 90DPTB0013ACL HHS 90DPTB0015ACL HHS 90DPTB0016NICHD NIH HHS K99 HD106060NINDS NIH HHS RF1 NS115268
6 · The paper itself

Abstract

objectiveTo evaluate the impact of COVID-19 pandemic exposure on changes in alcohol use and mood from years 1 to 2 after traumatic brain injury (TBI).

methodsWe used a difference-in-difference (DiD) study design to analyze data from 1,059 individuals with moderate-to-severe TBI enrolled in the TBI Model Systems (TBIMS) National Database. We defined COVID-19 pandemic exposure as participants who received their year 1 post-injury interviews prior to January 1, 2020, and their year 2 interview between April 1, 2020 and January 15, 2021. Pandemic-unexposed participants had both year 1 and 2 follow-up interviews before January 1, 2020. We measured current alcohol use as any past month alcohol use, average number of drinks per drinking occasion, and past month binge drinking. We measured depression symptoms using Patient Health Questionnaire-9, and anxiety symptoms using the Generalized Anxiety Disorder-7.

resultsWe found persons with TBI exposed to the pandemic had greater increases in the average number of drinks per occasion from year 1 to 2 post-injury compared to pandemic-unexposed individuals (β = 0.36, 95% CI: 0.16, 0.57, p = 0.001), with males, adults <65 years old, and Black and Hispanic subgroups showing the greatest increases in consumption. Though average consumption was elevated, changes in rates of any alcohol use or binge drinking by pandemic exposure were not observed. Overall, there were no significant changes in depressive and anxiety symptoms over time between pandemic exposed and unexposed groups; however, pandemic-exposed Hispanics with TBI reported significant increases in anxiety symptoms from year-1 to year-2 post-injury compared to pandemic-unexposed Hispanics (β = 2.35, 95% CI: 0.25, 4.47, p = 0.028).

conclusionAmong persons living with TBI, those exposed to the pandemic had significant increases in average alcohol consumption. Pandemic-exposed Hispanics with TBI had large elevations in anxiety symptoms, perhaps reflecting health inequities exacerbated by the pandemic, and suggesting a need for targeted monitoring of psychosocial distress.

Indexed as

Binge DrinkingBrain Injuries, TraumaticCOVID-19AdultAgedAlcohol DrinkingAnxietyHumansMalePandemics

Identifiers

PMID35390043
PMCPMC8989351
OpenAlexW4226189201

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.