Evidence map›Paper›PMID 35389997›Full record

ArticlePloS one2022

Inactivation of SARS-CoV-2 and influenza A virus by dry fogging hypochlorous acid solution and hydrogen peroxide solution.

Masahiro Urushidani, Akira Kawayoshi, Tomohiro Kotaki, Keiichi Saeki, Yasuko Mori, Masanori Kameoka

Abstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Ultrafine "dry vapor" hypochlorous: proof-of-concept disinfection application.Frontiers in cellular and infection microbiology · 2026
    Article
  2. Article
  3. Review
  4. Article
  5. A Virus Aerosol Chamber Study: The Impact of UVA, UVC, and HEnvironment & health (Washington, D.C.) · 2025
    Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Review
  11. Article
  12. Article
  13. Review
  14. Article
  15. The Biosafety Research Road Map: The Search for Evidence to Support Practices in the Laboratory-SARS-CoV-2.Applied biosafety : journal of the American Biological Safety Association · 2023
    Review
  16. Article
  17. Lignin: A Sustainable Antiviral Coating Material.ACS sustainable chemistry & engineering · 2022
    Article
  18. Article
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Masahiro UrushidaniDisinfection Division, H. Ikeuchi & Co., Ltd., Nishiwaki, Hyogo, Japan.
Akira KawayoshiDisinfection Division, H. Ikeuchi & Co., Ltd., Nishiwaki, Hyogo, Japan.
Tomohiro KotakiDivision of Global Infectious Diseases, Department of Public Health, Kobe University Graduate School of Health Sciences, Kobe, Hyogo, Japan.
Keiichi SaekiLaboratory of Microbiology and Immunology, Graduate School of Agricultural Science, Kobe University, Kobe, Hyogo, Japan.
Yasuko MoriDivision of Clinical Virology, Center for Infectious Diseases, Kobe University Graduate School of Medicine, Kobe, Hyogo, Japan.
Masanori KameokaDivision of Global Infectious Diseases, Department of Public Health, Kobe University Graduate School of Health Sciences, Kobe, Hyogo, Japan.ORCID 0000-0001-5525-9915

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the causative agent of coronavirus disease 2019 (COVID-19), is transmitted mainly by droplet or aerosol infection; however, it may also be transmitted by contact infection. SARS-CoV-2 that adheres to environmental surfaces remains infectious for several days. We herein attempted to inactivate SARS-CoV-2 and influenza A virus adhering to an environmental surface by dry fogging hypochlorous acid solution and hydrogen peroxide solution. SARS-CoV-2 and influenza virus were air-dried on plastic plates and placed into a test chamber for inactivation by the dry fogging of these disinfectants. The results obtained showed that the dry fogging of hypochlorous acid solution and hydrogen peroxide solution inactivated SARS-CoV-2 and influenza A virus in CT value (the product of the disinfectant concentration and contact time)-dependent manners. SARS-CoV-2 was more resistant to the virucidal effects of aerosolized hypochlorous acid solution and hydrogen peroxide solution than influenza A virus; therefore, higher concentrations of disinfectants or longer contact times were required to inactivate SARS-CoV-2 than influenza A virus. The present results provide important information for the development of a strategy that inactivates SARS-CoV-2 and influenza A virus on environmental surfaces by spatial fogging.

Indexed as

COVID-19DisinfectantsInfluenza A virusHumansHydrogen PeroxideHypochlorous AcidSARS-CoV-2Virus InactivationDisinfectantsHydrogen PeroxideHypochlorous Acid

Identifiers

PMID35389997
PMCPMC8989197

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.