ArticleScience (New York, N.Y.)2022
Cryptic and abundant marine viruses at the evolutionary origins of Earth's RNA virome.
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Article in Science (New York, N.Y.), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 149 papers.
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149citing papers in PubMed
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149 citing papers in PubMed, 256 citations in OpenAlex.
- Diversity of Antarctic sea ice and under-ice seawater RNA viruses.Applied and environmental microbiology · 2026Article
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- Elevation-structured viral ecological strategies along glacier-fed rivers on the Qinghai-Tibet Plateau.Nature communications · 2026Article
- Insights Gained by High-throughput Chromosome Conformation Capture (Hi-C) into the Viral Modulation of Methane Production in Anaerobic Digestion.Environmental science & technology · 2026Article
- Diversity and distinctive characteristics of the global RNA virome in urban and peri-urban environments.Nature communications · 2026Article
- Predicting the evolutionary and functional landscapes of viruses with a unified nucleotide-protein language model: LucaVirus.National science review · 2026Article
- A comprehensive RNA virome from molluscan transcriptomes reveals extensive diversity and modular genome evolution.Virologica Sinica · 2026Article
- Geographic genetic divergence and ecological viral communities shape the virome of Chilo suppressalis.Microbiome · 2026Article
- Longitudinal sampling of New Zealand cockles (Austrovenus stutchburyi) reveals high viral diversity and taxa-specific responses to environmental factors.FEMS microbiology ecology · 2026Article
- Screening metatranscriptomes for ultrastable RNA secondary structures reveals hidden bacteriophages and novel capsid nanomaterials.bioRxiv : the preprint server for biology · 2026Article
- Revealing deep evolutionary relationships between RNA viruses using predicted structural models of viral RNA polymerases.Molecular biology and evolution · 2026Article
- Microalga-virus-virophage coculture reveals co-infection of multi-virophages with a giant virus.Archives of virology · 2026Article
- Limited effect of short- to mid-term storage conditions on an Australian farmland soil RNA virome.Journal of virology · 2026Article
- A Unified Framework to Prioritize RNA Virus Cross-Species Transmission Risk Across an Expansive Host Landscape.Viruses · 2026Article
- Molecular architecture and diversity of StopGo/2A translational recoding.Proceedings of the National Academy of Sciences of the United States of America · 2026Article
- Cobamide-producing microbes as a model for understanding general nutritional interdependencies in soil food webs.Nature communications · 2026Article
- Metatranscriptomics reveals the horse gut RNA virome and a viral sharing network with human and domestic animals.Frontiers in veterinary science · 2026Article
- Viromics approaches for the study of viral diversity and ecology in microbiomes.Nature reviews. Genetics · 2026Review
- Metatranscriptomics reveals protistan and viral metabolic reprogramming of sinking particle microbiomes in Oyashio waters.ISME communications · 2026Article
- Phage evolutionary relationships emerge from protein language model-based proteome representation.NAR genomics and bioinformatics · 2025Article
89 more citing papers are in PubMed but not listed here.
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Authors and funding
58 authors at 5 institutions in 4 countries.
Ahmed A Zayed *Department of Microbiology, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-2793-2679
James M Wainaina *Department of Microbiology, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-7233-4793
Guillermo Dominguez-Huerta *Department of Microbiology, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0001-9799-6139
Eric PelletierGénomique Métabolique, Genoscope, Institut François-Jacob, CEA, CNRS, Univ Evry, Université Paris-Saclay, 91000 Evry, France.ORCID 0000-0003-4228-1712
Jiarong GuoDepartment of Microbiology, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-6903-5418
Mohamed MohssenDepartment of Microbiology, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-7687-7007
Funing TianDepartment of Microbiology, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-7217-3125
Akbar Adjie PratamaDepartment of Microbiology, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-1079-744X
Benjamin BolducDepartment of Microbiology, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-2420-0755
Olivier ZablockiDepartment of Microbiology, Ohio State University, Columbus, OH 43210, USA.
Dylan CroninDepartment of Microbiology, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-3528-9866
Lindsey SoldenDepartment of Microbiology, Ohio State University, Columbus, OH 43210, USA.
Erwan DelageResearch Federation for the Study of Global Ocean Systems Ecology and Evolution, FR2022/Tara Oceans GOSEE, 75016 Paris, France.ORCID 0000-0002-7653-5111
Adriana AlbertiGénomique Métabolique, Genoscope, Institut François-Jacob, CEA, CNRS, Univ Evry, Université Paris-Saclay, 91000 Evry, France.ORCID 0000-0003-3372-9423
Jean-Marc AuryGénomique Métabolique, Genoscope, Institut François-Jacob, CEA, CNRS, Univ Evry, Université Paris-Saclay, 91000 Evry, France.ORCID 0000-0003-1718-3010
Quentin CarradecGénomique Métabolique, Genoscope, Institut François-Jacob, CEA, CNRS, Univ Evry, Université Paris-Saclay, 91000 Evry, France.ORCID 0000-0003-4612-8678
Corinne da SilvaGénomique Métabolique, Genoscope, Institut François-Jacob, CEA, CNRS, Univ Evry, Université Paris-Saclay, 91000 Evry, France.ORCID 0000-0002-7618-7831
Karine LabadieGénomique Métabolique, Genoscope, Institut François-Jacob, CEA, CNRS, Univ Evry, Université Paris-Saclay, 91000 Evry, France.ORCID 0000-0001-7467-8509
Julie PoulainGénomique Métabolique, Genoscope, Institut François-Jacob, CEA, CNRS, Univ Evry, Université Paris-Saclay, 91000 Evry, France.ORCID 0000-0002-8744-3116
Hans-Joachim RuscheweyhDepartment of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH Zurich, Zurich, Switzerland.ORCID 0000-0001-7473-6086
Guillem SalazarDepartment of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH Zurich, Zurich, Switzerland.
Elan ShatoffDepartment of Physics, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0003-4632-2286
Tara Oceans Coordinators‡
Ralf BundschuhThe Interdisciplinary Biophysics Graduate Program, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-6699-8614
Kurt FredrickDepartment of Microbiology, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0002-5115-6641
Laura S KubatkoDepartment of Evolution, Ecology, and Organismal Biology, Ohio State University, Columbus, OH 43210, USA.
Samuel ChaffronResearch Federation for the Study of Global Ocean Systems Ecology and Evolution, FR2022/Tara Oceans GOSEE, 75016 Paris, France.ORCID 0000-0001-5903-617X
Alexander I CulleyDépartement de Biochimie, Microbiologie et Bio-informatique, Université Laval, Québec, Québec G1V 0A6, Canada.ORCID 0000-0001-6639-9112
Shinichi SunagawaDepartment of Biology, Institute of Microbiology and Swiss Institute of Bioinformatics, ETH Zurich, Zurich, Switzerland.ORCID 0000-0003-3065-0314
Jens H KuhnIntegrated Research Facility at Fort Detrick, National Institute of Allergy and Infectious Diseases, National Institutes of Health, Fort Detrick, Frederick, MD 21702, USA.ORCID 0000-0002-7800-6045
Patrick WinckerGénomique Métabolique, Genoscope, Institut François-Jacob, CEA, CNRS, Univ Evry, Université Paris-Saclay, 91000 Evry, France.
Matthew B SullivanDepartment of Microbiology, Ohio State University, Columbus, OH 43210, USA.ORCID 0000-0001-8398-8234
Silvia G Acinas
Marcel Babin
Peer Bork
Emmanuel Boss
Chris Bowler
Guy Cochrane
Colomban de Vargas
Gabriel Gorsky
Lionel Guidi
Nigel Grimsley
Pascal Hingamp
Daniele Iudicone
Olivier Jaillon
Stefanie Kandels
Lee Karp-Boss
Eric Karsenti
Fabrice Not
Hiroyuki Ogata
Nicole Poulton
Stéphane Pesant
Christian Sardet
Sabrinia Speich
Lars Stemmann
Matthew B Sullivan
Shinichi Sungawa
Patrick Wincker
The Ohio State University · USCentre National de la Recherche Scientifique · FRSIB Swiss Institute of Bioinformatics · CHNational Institutes of Health · USUniversité Laval · CA
Funding
Molecular analysis of accurate ribosomal translocationR01GM072528 · NIGMS · OHIO STATE UNIVERSITY · PI Kurt L Fredrick · 2005 to 2026
$5.8MNIAID NIH HHS HHSN272201800013C
Abstract
Whereas DNA viruses are known to be abundant, diverse, and commonly key ecosystem players, RNA viruses are insufficiently studied outside disease settings. In this study, we analyzed ≈28 terabases of Global Ocean RNA sequences to expand Earth's RNA virus catalogs and their taxonomy, investigate their evolutionary origins, and assess their marine biogeography from pole to pole. Using new approaches to optimize discovery and classification, we identified RNA viruses that necessitate substantive revisions of taxonomy (doubling phyla and adding >50% new classes) and evolutionary understanding. "Species"-rank abundance determination revealed that viruses of the new phyla "
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Genome, ViralRNA VirusesVirusesBiological EvolutionEcosystemOceans and SeasPhylogenyRNAViromeRNA
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