Evidence map›Paper›PMID 35389566›Full record

ArticleClinical and translational medicine2022

Key role of quorum-sensing mutations in the development of Staphylococcus aureus clinical device-associated infection.

Lei He, Feiyang Zhang, Ying Jian, Huiying Lv, Musha Hamushan, Junlan Liu, Yao Liu, Hua Wang, Jin Tang, Pei Han and 5 more

Abstract readLetter
In one paragraph

Article in Clinical and translational medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Article
  5. Journal of bacteriology · 2025
    Review
  6. Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  7. Article
  8. Review
  9. Review
  10. Methicillin Resistance Elements in the Canine PathogenAntibiotics (Basel, Switzerland) · 2024
    Article
  11. Identification ofVirulence · 2023
    Article
  12. Review
  13. Article
  14. Chemical and biomolecular insights into theIsrael journal of chemistry · 2023
    Article
  15. Article
  16. Article
  17. Critical Assessment of the Prospects of Quorum-Quenching Therapy forInternational journal of molecular sciences · 2023
    Review
  18. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Lei HeDepartment of Laboratory Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Feiyang ZhangDepartment of Orthopedics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Ying JianDepartment of Laboratory Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Huiying LvDepartment of Laboratory Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Musha HamushanDepartment of Orthopedics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Junlan LiuDepartment of Laboratory Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Yao LiuDepartment of Laboratory Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Hua WangDepartment of Laboratory Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Jin TangClinical Laboratory Department, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Pei HanDepartment of Orthopedics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Dylan J BurginPathogen Molecular Genetics Section, Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Bethesda, Maryland, USA.
Seth W DickeyPathogen Molecular Genetics Section, Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Bethesda, Maryland, USA.
Hao ShenDepartment of Orthopedics, Shanghai Jiao Tong University Affiliated Sixth People's Hospital, Shanghai, China.
Min LiDepartment of Laboratory Medicine, Ren Ji Hospital, Shanghai Jiao Tong University School of Medicine, Shanghai, China.
Michael OttoPathogen Molecular Genetics Section, Laboratory of Bacteriology, National Institute of Allergy and Infectious Diseases, US National Institutes of Health, Bethesda, Maryland, USA.ORCID 0000-0002-2222-4115

Funding

Staphylococcal pathogenesisZIAAI000904 · NIAID · NATIONAL INSTITUTE OF ALLERGY AND INFECTIOUS DISEASES · PI OTTO, MICHAEL · 2009 to 2025
$22.6M
Staphylococcus Epidermidis Biofilm FormationZ01AI000904 · NIAID · NIAID EXTRAMURAL ACTIVITIES · PI OTTO, MICHAEL J · 2002 to 2008
$2.5M
Intramural NIH HHS Z01 AI000904Intramural NIH HHS ZIA AI000904
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

Staphylococcal InfectionsStaphylococcus aureusHumansMutationQuorum Sensing

Identifiers

PMID35389566
PMCPMC8989080

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.