ArticleJAMA otolaryngology-- head & neck surgery2022
Association Between Meniere Disease and Migraine.
Article in JAMA otolaryngology-- head & neck surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 25 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
25 citing papers in PubMed, 1 synthesis or guideline pooled it, 43 citations in OpenAlex.
- Genome-wide analysis implicates inner ear development in Ménière disease.American journal of human genetics · 2026Pooled it
- Meniere's Disease and Migraine: Effect of Migraine Medications on Symptoms of Meniere's Disease.The Laryngoscope · 2026Article
- Review
- Menière's disease clinical subtypes and baseline characteristics in a Dutch patient cohort.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026Article
- Causal cross-trait mapping at single-cell resolution identifies shared immunogenetic drivers of migraine and Meniere's disease.The journal of headache and pain · 2026Article
- Genome-wide analysis implicates inner ear development in Ménière's disease.medRxiv : the preprint server for health sciences · 2026Article
- Sex and Gender Aspects in Vestibular Disorders: Current Knowledge and Emerging Perspectives-A Systematic Review.Diagnostics (Basel, Switzerland) · 2026Review
- The diagnostic significance and value of vestibular function testing combined with MRI in Meniere's disease.Head & face medicine · 2025Article
- Trigeminal Nerve and Vestibular System: Update on Pathophysiological and Clinical Links.Audiology research · 2025Review
- Migraine with and without aura-two distinct entities? A narrative review.The journal of headache and pain · 2025Review
- Immunological mechanisms in Meniere's disease.Frontiers in immunology · 2025Review
- Did Martin Luther suffer from vestibular migraine?European journal of neurology · 2024Article
- Epidemiological Evidence for Upper Respiratory Infections as a Potential Risk Factor for Meniere's Disease: A Korean National Health Sample Cohort Study.Microorganisms · 2024Article
- Article
- Mendelian randomization analysis does not reveal a causal association between migraine and Meniere's disease.Frontiers in neurology · 2024Article
- Identifying Predictors of Treatment Response in Meniere's Disease: A Clinical Severity Staging System.Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery · 2024Article
- Can head sway patterns differentiate between patients with Meniere's disease vs. peripheral vestibular hypofunction?Frontiers in neurology · 2024Article
- Neurological update: neuro-otology 2023.Journal of neurology · 2023Article
- Cerebral Small Vessel Disease in Elderly Patients With Menière's Disease.Otology & neurotology open · 2023Article
- Recent advances in understanding molecular bases of Ménière's disease.Faculty reviews · 2023Review
Corrections and comments
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Authors and funding
9 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Importance: A connection between Meniere disease (MD) and migraine has been proposed, but the temporal association remains unknown. Objective: To examine the bidirectional association of MD with migraine. Design, Setting, and Participants: This case-control study included participants 40 years or older from the Korean National Health Insurance Service Health Screening Cohort from 2002 to 2015. Main Outcomes and Measures: A total of 6919 patients with MD were matched with 27 676 control participants without MD for age, sex, income, region of residence, and index date. The incidence of migraine was analyzed in the MD and matched groups using a stratified Cox proportional hazard regression model. In addition, 35 889 patients with migraine were matched with 71 778 control participants without migraine. The incidence of MD was analyzed using a stratified Cox proportional hazard regression model. Results: Of 142 262 total participants, 94 611 (66.5%) were women. Migraine occurred in 695 of 6919 patients with MD (10.0%) and 970 of 27 676 matched control participants (3.5%). The MD group demonstrated a 2.22-fold higher risk of migraine than the matched control group (95% CI, 1.99-2.49). Meniere disease was present in 1098 of 35 889 patients with migraine (3.1%) and 781 of 71 778 matched control participants (1.1%). The migraine group had a 1.95-fold higher risk of MD than the matched control group (95% CI, 1.77-2.15). Conclusions and Relevance: The results of this case-control study suggest that patients with MD had a greater risk of migraine occurrence. Furthermore, patients with migraine had a higher risk of MD. Based on the bidirectional association, therapeutics for migraine could potentially be applied to MD and vice versa.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.