Evidence map›Paper›PMID 35389295›Full record

ArticleJournal of investigative medicine high impact case reports

Lupus Pneumonitis: Case Report of a Rare Manifestation of Neonatal Lupus.

Ricardo Barreto Mota, Nuno Rodrigues Santos, Paulo Éden, Mariana Rodrigues, Iva Brito, Henrique Soares

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of investigative medicine high impact case reports. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.5field-weighted citation impact, top 35% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Lupus pneumonitis in neonatal lupus: a case report.Journal of medical case reports · 2025
    Article
  2. [Research progress on the manifestations and prognosis of neonatal lupus erythematosus in various systems].Zhongguo dang dai er ke za zhi = Chinese journal of contemporary pediatrics · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Ricardo Barreto MotaNeonatology Department, Centro Hospitalar Universitário de São João, Porto, Portugal.ORCID 0000-0001-7145-7073
Nuno Rodrigues SantosNeonatology Department, Centro Hospitalar Universitário de São João, Porto, Portugal.
Paulo ÉdenPediatric Cardiology Department, Centro Hospitalar Universitário São João, Porto, Portugal.
Mariana RodriguesPediatric and Young Adult Rheumatology Unit, Pediatrics Department, Centro Hospitalar Universitário São João, Porto, Portugal.
Iva BritoPediatric and Young Adult Rheumatology Unit, Pediatrics Department, Centro Hospitalar Universitário São João, Porto, Portugal.
Henrique SoaresNeonatology Department, Centro Hospitalar Universitário de São João, Porto, Portugal.
Hospital de São João · PTUniversidade do Porto · PT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal lupus is a rare entity, secondary to placental transfer of antibodies from mothers with immune-mediated conditions. While pulmonary involvement is common in lupus, its incidence in neonates is extremely rare, with very few cases being reported in the literature. The authors report a case of a neonate whose mother was diagnosed with systemic lupus erythematosus, with a prenatal diagnosis of third-degree atrioventricular block. While initially admitted in the neonatal intensive care unit with no need for organ support, he presented progressive respiratory failure, initially attributed to sepsis. Favorable clinical progression after pacemaker placement allowed ventilatory weaning, but respiratory failure was again apparent. Chest computer tomography revealed areas of ground-glass lesions, raising the suspicion for lupus pneumonitis. He was started on immunoglobulin and corticosteroids, with clinical improvement. The authors consider this case to be relevant due to the rarity of acute lupus pneumonitis in neonates, alerting that it must be considered a differential diagnosis in neonates with prolonged ventilator dependency.

Indexed as

Lupus Erythematosus, SystemicPneumoniaRespiratory InsufficiencyFemaleHumansInfant, NewbornMalePlacentaPregnancyatrioventricular blockimmunoglobulinsneonatal systemic lupus erythematosuspneumonitis

Identifiers

PMID35389295
PMCPMC9016583
OpenAlexW4223557317

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.