Evidence map›Paper›PMID 35389256›Full record

ArticleJournal of bacteriology2022

Distinct Subcellular Localization of a Type I CRISPR Complex and the Cas3 Nuclease in Bacteria.

Sutharsan Govindarajan, Adair Borges, Shweta Karambelkar, Joseph Bondy-Denomy

Open access · greenAbstract read
In one paragraph

Article in Journal of bacteriology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. KilR ofmSphere · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Sutharsan GovindarajanDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA.
Adair BorgesDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA.
Shweta KarambelkarDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA.
Joseph Bondy-DenomyDepartment of Microbiology and Immunology, University of California, San Francisco, San Francisco, California, USA.ORCID 0000-0002-4909-9481
University of California, San Francisco · US

Funding

Microbial Pathogenesis and Host DefenseT32AI060537 · NIAID · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI Joanne N. Engel · 2004 to 2026
$6.5M
Discovering New Roles for CRISPR-Cas in Bacterial PathogenesisDP5OD021344 · OD · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BONDY-DENOMY, JOSEPH · 2015 to 2019
$2.1M
Uncovering the mechanism and role of a widespread anti-CRISPR-Cas9 proteinR01GM127489 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN FRANCISCO · PI BONDY-DENOMY, JOSEPH · 2018 to 2022
$1.7M
NIAID NIH HHS T32 AI060537NIGMS NIH HHS R01 GM127489NIH HHS DP5 OD021344Sandler Foundation
6 · The paper itself

Abstract

Clustered regularly interspaced short palindromic repeats (CRISPR)-CRISPR-associated (Cas) systems are prokaryotic adaptive immune systems that have been well characterized biochemically, but

Indexed as

CRISPR-Associated ProteinsBacteriaCRISPR-Cas SystemsDNA HelicasesEndonucleasesCRISPR-Associated ProteinsDNA HelicasesEndonucleasesanti-CRISPRbacterial cell biologybacteriophagesCRISPR-Casspatial organization

Identifiers

PMID35389256
PMCPMC9112876
OpenAlexW4226148854

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.