Evidence map›Paper›PMID 35389255›Full record

ArticleJournal of bacteriology2022

Phage Infection Restores PQS Signaling and Enhances Growth of a Pseudomonas aeruginosa

Nina Molin Høyland-Kroghsbo, Bonnie L Bassler

Open access · hybridAbstract read
In one paragraph

Article in Journal of bacteriology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 14 citations in OpenAlex.

  1. Review
  2. Article
  3. The H-NS homologues MvaT and MvaU repress CRISPR-Cas inPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2025
    Article
  4. Disruption ofMicrobiology (Reading, England) · 2025
    Article
  5. Review
  6. Review
  7. Article
  8. Swarming ofBiophysics reviews · 2023
    Review
  9. The IsolatePlants (Basel, Switzerland) · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 2 institutions in 1 country.

Nina Molin Høyland-KroghsboDepartment of Molecular Biology, Princeton Universitygrid.16750.35, Princeton, New Jersey, USA.ORCID 0000-0001-5904-8859
Bonnie L BasslerDepartment of Molecular Biology, Princeton Universitygrid.16750.35, Princeton, New Jersey, USA.ORCID 0000-0002-0043-746X
Howard Hughes Medical Institute · USPrinceton University · US

Funding

Intra- and Inter- Species Communication in BacteriaR37GM065859 · NIGMS · PRINCETON UNIVERSITY · PI BASSLER, BONNIE L · 2016 to 2025
$3.4M
HHS | National Institutes of Health (NIH) 2R37GM065859Howard Hughes Medical InstituteLundbeckfonden (Lundbeck Foundation) R220-2016-860Lundbeckfonden (Lundbeck Foundation) R264-2017-3936National Science Foundation (NSF) MCB-2043238NIGMS NIH HHS R37 GM065859
6 · The paper itself

Abstract

Chemical communication between bacteria and between bacteria and the bacteriophage (phage) viruses that prey on them can shape the outcomes of phage-bacterial encounters. Quorum sensing (QS) is a bacterial cell-to-cell communication process that promotes collective undertaking of group behaviors. QS relies on the production, release, accumulation, and detection of signal molecules called autoinducers. Phages can exploit QS-mediated communication to manipulate their hosts and maximize their own survival. In the opportunistic pathogen Pseudomonas aeruginosa, the LasI/R QS system induces the RhlI/R QS system, and in opposing manners, these two systems control the QS system that relies on the autoinducer called PQS. A P. aeruginosa Δ

Indexed as

BacteriophagesQuorum SensingBacterial ProteinsPseudomonas aeruginosaVirulence FactorsBacterial ProteinsVirulence FactorsbacteriophagePseudomonasquorum sensingvirulence

Identifiers

PMID35389255
PMCPMC9112912
OpenAlexW4225341247

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.