ReviewHead and neck pathology2022
Ghost Cell Odontogenic Carcinoma Arising in a Previous Calcifying Odontogenic Cyst: A Case Report and Review of Literature.
Review in Head and neck pathology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.
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Who cites it
8 citing papers in PubMed.
- Evidence from intra-patient progression indicates adenoid ameloblastoma as a phenotypic variant of dentinogenic ghost cell tumor.Virchows Archiv : an international journal of pathology · 2026Article
- Ghost Cell Odontogenic Carcinoma: Case Series and Literature Review.Head and neck pathology · 2025Review
- Ghost Cell Odontogenic Carcinoma of the Anterior Maxilla with ARID1A Mutation: A Case Report and Literature Review.Head and neck pathology · 2025Review
- Dentinogenic Ghost Cell Tumor in an Elderly Female: A Rare Case Report.Case reports in dentistry · 2025Article
- Challenging pitfalls in frozen section pathology: a case of mandible ghost cell odontogenic carcinoma and the literature review.BMC oral health · 2024Article
- Article
- A Current Review of Machine Learning and Deep Learning Models in Oral Cancer Diagnosis: Recent Technologies, Open Challenges, and Future Research Directions.Diagnostics (Basel, Switzerland) · 2023Review
- Case report: Ghost cell odontogenic carcinoma in a dog: diagnostics and surgical outcome.Frontiers in veterinary science · 2023Article
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Authors and funding
9 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Ghost cell odontogenic carcinoma (GCOC) is a rare malignant tumor of odontogenic origin, with only about 50 cases reported in the English literature so far. Histologically, it is characterized by ghost cells, dentinoid deposits, high grade malignant cellular features, and areas of necrosis and invasion. Having common histological features with other odontogenic ghost cell lesions (OGCL) like calcifying odontogenic cyst (COC) and dentinogenic ghost cell tumors, it is crucial to recognize GCOC malignant features, as it can be destructive and invasive, sometimes showing distant metastases and high recurrence rate. For this reason, it may entail more aggressive surgical approach and multimodal therapeutic regimen. Here we present a case report of GCOC arising in a previous COC, treated with surgical excision that showed persistence and recurrence after two years. The clinical and histological features of this rare occurrence are presented, in addition to the surgical approach, and a summary of literature review of OGCL.
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