Evidence map›Paper›PMID 35389104›Full record

ArticleCellular and molecular life sciences : CMLS2022

Structural mechanism of TRPM7 channel regulation by intracellular magnesium.

Eva Schmidt, Chamali Narangoda, Wolfgang Nörenberg, Miyuki Egawa, Anna Rössig, Marion Leonhardt, Michael Schaefer, Susanna Zierler, Maria G Kurnikova, Thomas Gudermann and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Cellular and molecular life sciences : CMLS, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
2.7field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 27 citations in OpenAlex.

  1. Review
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  9. Review
  10. Article
  11. Review
  12. Unlocking TRPM7 interactions: A database-driven quest.Computational and structural biotechnology journal · 2025
    Review
  13. Article
  14. Article
  15. TRPM channels in health and disease.Nature reviews. Nephrology · 2024
    Review
  16. Article
  17. Article
  18. PRL-1/2 phosphatases control TRPM7 magnesium-dependent function to regulate cellular bioenergetics.Proceedings of the National Academy of Sciences of the United States of America · 2023
    Article
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 6 institutions in 4 countries.

Eva SchmidtWalther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.
Chamali NarangodaChemistry Department, Carnegie Mellon University, Pittsburgh, PA, USA.
Wolfgang NörenbergRudolf-Boehm Institute of Pharmacology and Toxicology, Leipzig University, Leipzig, Germany.
Miyuki EgawaWalther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.
Anna RössigWalther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.
Marion LeonhardtRudolf-Boehm Institute of Pharmacology and Toxicology, Leipzig University, Leipzig, Germany.
Michael SchaeferRudolf-Boehm Institute of Pharmacology and Toxicology, Leipzig University, Leipzig, Germany.
Susanna ZierlerWalther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany.
Maria G Kurnikova *Chemistry Department, Carnegie Mellon University, Pittsburgh, PA, USA.
Thomas GudermannWalther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany. thomas.gudermann@lrz.uni-muenchen.de.
Vladimir ChubanovWalther-Straub Institute of Pharmacology and Toxicology, LMU Munich, Munich, Germany. vladimir.chubanov@lrz.uni-muenchen.de.ORCID http://orcid.org/0000-0002-6042-4193
Leipzig University · DELudwig-Maximilians-Universität München · DECarnegie Mellon University · USCentre of Experimental Medicine of the Slovak Academy of Sciences · SKJohannes Kepler University of Linz · ATLMU Klinikum · DE

Funding

Structure and Function of AMPA subtype ionotropic glutamate receptorsR01NS083660 · NINDS · COLUMBIA UNIVERSITY HEALTH SCIENCES · PI KURNIKOVA, MARIA G, SOBOLEVSKY, ALEXANDER · 2013 to 2022
$4.3M
California Department of Fish and Game Research Training Group 2338DFG TRP 152 P 14DFG TRP152 P15DFG TRP152 P18DFG TRR 152 P15National Science Foundation NSF 1818213NIH HHS R01NS083660NINDS NIH HHS R01 NS083660
6 · The paper itself

Abstract

Zn

Indexed as

TRPM Cation ChannelsAnimalsCations, DivalentMagnesiumMicePhosphotransferasesCations, DivalentMagnesiumPhosphotransferasesTrpm7 protein, mouseTRPM Cation ChannelsATPMagnesiumMolecular dynamics simulationsPIP2TRP channelsTRPM7

Identifiers

PMID35389104
PMCPMC8989868
OpenAlexW4223597924

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.