Evidence map›Paper›PMID 35389067›Full record

ArticleApplied microbiology and biotechnology2022

Beyond the cyclopropyl ring formation: fungal Aj_EasH catalyzes asymmetric hydroxylation of ergot alkaloids.

Chunyan An, Fangfang Zhu, Yongpeng Yao, Kexin Zhang, Wei Wang, Jun Zhang, Guangzheng Wei, Yue Xia, Qiang Gao, Shu-Shan Gao

Abstract read
PubMed Publisher
In one paragraph

Article in Applied microbiology and biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.6field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 1 country.

Chunyan An *Key Laboratory of Industrial Fermentation Microbiology of Ministry of Education, Biotechnology College of Tianjin University of Science and Technology, Tianjin, 300457, China. ancy@im.ac.cn.ORCID http://orcid.org/0000-0001-9918-5903
Fangfang Zhu *Key Laboratory of Industrial Fermentation Microbiology of Ministry of Education, Biotechnology College of Tianjin University of Science and Technology, Tianjin, 300457, China.
Yongpeng Yao *State Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.ORCID http://orcid.org/0000-0002-6084-1683
Kexin ZhangState Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
Wei WangState Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.ORCID http://orcid.org/0000-0002-4558-4738
Jun ZhangState Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
Guangzheng WeiState Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
Yue XiaState Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China.
Qiang GaoKey Laboratory of Industrial Fermentation Microbiology of Ministry of Education, Biotechnology College of Tianjin University of Science and Technology, Tianjin, 300457, China. gaoqiang@tust.edu.cn.
Shu-Shan GaoState Key Laboratory of Microbial Resources, Institute of Microbiology, Chinese Academy of Sciences, Beijing, 100101, People's Republic of China. gaoss@im.ac.cn.ORCID http://orcid.org/0000-0001-6335-2052
Chinese Academy of Sciences · CNTianjin University of Science and Technology · CN

Funding

Innovative Cross Team project of CAS JCTD-2019-06National Natural Science Foundation of China 31872614National Natural Science Foundation of China 32001036National Research and Development Program of China 2018YFA0901600National Research and Development Program of China 2019YFA0905100the Senior User Project of RV KEXUE, Center for Ocean Mega-Science, CAS KEXUE2019GZ05Youth Innovation Promotion Association of the Chinese Academy of Sciences 2019090
6 · The paper itself

Abstract

Ergot alkaloids (EAs) are among the most important bioactive natural products. Fe

Indexed as

Ergot AlkaloidsAlpha-Ketoglutarate-Dependent Dioxygenase FTOFerrous CompoundsHydroxylationMolecular Docking SimulationAlpha-Ketoglutarate-Dependent Dioxygenase FTOErgot AlkaloidsFerrous CompoundsAj_EasHErgot alkaloidHydroxylasesPromiscuity

Identifiers

PMID35389067
OpenAlexW4225394062

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.