Evidence map›Paper›PMID 35388625›Full record

ArticleAlzheimer's & dementia : the journal of the Alzheimer's Association2023

Neighborhood disadvantage and dementia incidence in a cohort of Asian American and non-Latino White older adults in Northern California.

Taylor M Mobley, Crystal Shaw, Eleanor Hayes-Larson, Joseph Fong, Paola Gilsanz, Gilbert C Gee, Ron Brookmeyer, Rachel A Whitmer, Joan A Casey, Elizabeth Rose Mayeda

Open access · greenAbstract read
In one paragraph

Article in Alzheimer's & dementia : the journal of the Alzheimer's Association, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
26citing papers in PubMed, 1 pooled it
4.5field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

26 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

  1. Pooled it
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  12. Neighborhood disadvantage and the incidence of dementia in US Black women.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
  13. Accountable care organizations and Medicare payments for residents with ADRD in disadvantaged neighborhoods.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2025
    Article
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  17. Deriving life-course residential histories in brain bank cohorts: A feasibility study.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
    Article
  18. Article
  19. Neighborhood disadvantage reduces cognitive reserve independent of neuropathologic change.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2024
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 1 country.

Taylor M MobleyDepartment of Epidemiology, University of California, Los Angeles Fielding School of Public Health, Los Angeles, California, USA.
Crystal ShawDepartment of Epidemiology, University of California, Los Angeles Fielding School of Public Health, Los Angeles, California, USA.
Eleanor Hayes-LarsonDepartment of Epidemiology, University of California, Los Angeles Fielding School of Public Health, Los Angeles, California, USA.
Joseph FongDepartment of Epidemiology, University of California, Los Angeles Fielding School of Public Health, Los Angeles, California, USA.
Paola GilsanzKaiser Permanente Division of Research, Oakland, California, USA.
Gilbert C GeeDepartment of Community Health Sciences, University of California, Los Angeles Fielding School of Public Health, Los Angeles, California, USA.
Ron BrookmeyerDepartment of Biostatistics, University of California, Los Angeles Fielding School of Public Health, Los Angeles, California, USA.
Rachel A WhitmerKaiser Permanente Division of Research, Oakland, California, USA.
Joan A CaseyDepartment of Environmental Health Sciences, Columbia University Mailman School of Public Health, New York, New York, USA.
Elizabeth Rose MayedaDepartment of Epidemiology, University of California, Los Angeles Fielding School of Public Health, Los Angeles, California, USA.
University of California, Los Angeles · USUniversity of California, San Francisco · USAlzheimer’s Disease Neuroimaging Initiative · USColumbia University · US

Funding

UC Davis Alzheimer's Disease Core CenterP30AG010129 · NIA · UNIVERSITY OF CALIFORNIA DAVIS · PI DECARLI, CHARLES · 1991 to 2020
$28.3M
UC Davis Alzheimer's Disease Research CenterP30AG072972 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI Charles DeCarli, Rachel A Whitmer · 2021 to 2026
$25.2M
Lifecourse health, cerebral pathology and ethnic disparities in dementia (KHANDLE Study)R01AG052132 · NIA · UNIVERSITY OF CALIFORNIA AT DAVIS · PI GILSANZ, PAOLA, GLYMOUR, MEDELLENA MARIA · 2021 to 2025
$18.0M
Scientific and Technical CoreP2CHD041022 · NICHD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Martha Jane Bailey · 2016 to 2026
$6.9M
Alzheimer’s disease and related dementias in a diverse cohort of Asian AmericansR01AG063969 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAYEDA, ELIZABETH ROSE · 2019 to 2022
$2.0M
Contributions of educational quality and occupational complexity on racial and ethnic inequities in brain health and Alzheimer's disease and related dementiaR01AG066132 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI GILSANZ, PAOLA · 2019 to 2023
$2.0M
Glycemic Control and Dementia: The Role of Pharmacotherapy and Vascular ComplicationsR01AG067199 · NIA · KAISER FOUNDATION RESEARCH INSTITUTE · PI GILSANZ, PAOLA · 2020 to 2024
$1.9M
Racial Disparities in Alzheimer's Disease and Related Dementias: The Role of Blood Pressure Throughout AdulthoodR00AG053410 · NIA · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MAYEDA, ELIZABETH ROSE · 2018 to 2020
$710k
NIA NIH HHS P30 AG010129NIA NIH HHS P30 AG072972NIA NIH HHS R00 AG053410NIA NIH HHS R01 AG052132NIA NIH HHS R01 AG063969NIA NIH HHS R01 AG066132NIA NIH HHS R01 AG067199NICHD NIH HHS P2C HD041022
6 · The paper itself

Abstract

introductionSome evidence suggests that neighborhood socioeconomic disadvantage is associated with dementia-related outcomes. However, prior research is predominantly among non-Latino Whites.

methodsWe evaluated the association between neighborhood disadvantage (Area Deprivation Index [ADI]) and dementia incidence in Asian American (n = 18,103) and non-Latino White (n = 149,385) members of a Northern California integrated health care delivery system aged 60 to 89 at baseline. Race/ethnicity-specific Cox proportional hazards models adjusted for individual-level age, sex, socioeconomic measures, and block group population density estimated hazard ratios (HRs) for dementia.

resultsAmong non-Latino Whites, ADI was associated with dementia incidence (most vs. least disadvantaged ADI quintile HR = 1.09, 95% confidence interval [CI] = 1.02-1.15). Among Asian Americans, associations were close to null (e.g., most vs. least disadvantaged ADI quintile HR = 1.01, 95% CI = 0.85-1.21). DISCUSSION: ADI was associated with dementia incidence among non-Latino Whites but not Asian Americans. Understanding the potentially different mechanisms driving dementia incidence in these groups could inform dementia prevention efforts.

Indexed as

DementiaHealth InequitiesAgedAsianCaliforniaHumansIncidenceNeighborhood CharacteristicsResidence CharacteristicsWhitedementiaincidenceneighborhood disadvantageracial/ethnic disparitiessocial determinants

Identifiers

PMID35388625
PMCPMC9535033
OpenAlexW4226191056

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.