Evidence map›Paper›PMID 35388591›Full record

ArticleInfluenza and other respiratory viruses2022

Non-invasive genomics of respiratory pathogens infecting wild great apes using hybridisation capture.

Livia V Patrono, Caroline Röthemeier, Leonce Kouadio, Emmanuel Couacy-Hymann, Roman M Wittig, Sébastien Calvignac-Spencer, Fabian H Leendertz

Open access · goldAbstract read
In one paragraph

Article in Influenza and other respiratory viruses, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.2field-weighted citation impact, top 21% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 9 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 2 countries.

Livia V PatronoProject Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Berlin, Germany.ORCID 0000-0003-3978-3607
Caroline RöthemeierProject Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Berlin, Germany.
Leonce KouadioLaboratoire National d'Appui au Développement Agricole/Laboratoire Central de Pathologie Animale, Bingerville, Côte d'Ivoire.
Emmanuel Couacy-HymannLaboratoire National d'Appui au Développement Agricole/Laboratoire Central de Pathologie Animale, Bingerville, Côte d'Ivoire.
Roman M WittigDepartment of Primatology, Max Planck Institute for Evolutionary Anthropology, Leipzig, Germany.
Sébastien Calvignac-SpencerProject Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Berlin, Germany.
Fabian H LeendertzProject Group Epidemiology of Highly Pathogenic Microorganisms, Robert Koch Institute, Berlin, Germany.
Robert Koch Institute · DELaboratoire National d'Appui au Développement Agricole · CIMax Planck Institute for Evolutionary Anthropology · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Human respiratory pathogens have repeatedly caused lethal outbreaks in wild great apes across Africa, leading to population declines. Nonetheless, our knowledge of potential genomic changes associated with pathogen introduction and spread at the human-great ape interface remains sparse. Here, we made use of target enrichment coupled with next generation sequencing to non-invasively investigate five outbreaks of human-introduced respiratory disease in wild chimpanzees living in Taï National Park, Ivory Coast. By retrieving 34 complete viral genomes and three distinct constellations of pneumococcal virulence factors, we provide genomic insights into these spillover events and describe a framework for non-invasive genomic surveillance in wildlife.

Indexed as

Ape DiseasesHominidaeAnimalsAnimals, WildGenomicsHumansPan troglodytesnon-invasive health monitoringpathogen genomicsrespiratory diseasewild great apes

Identifiers

PMID35388591
PMCPMC9343332
OpenAlexW4224235921

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.