Evidence map›Paper›PMID 35388526›Full record

ArticleJournal of veterinary internal medicine2022

Quantification of gastroesophageal regurgitation in brachycephalic dogs.

Carla Appelgrein, Giselle Hosgood, Mary Thompson, Flaminia Coiacetto

Open access · goldAbstract read
In one paragraph

Article in Journal of veterinary internal medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Carla AppelgreinSchool of Veterinary Medicine, Murdoch University, Perth, Western Australia, Australia.ORCID https://orcid.org/0000-0003-2507-9790
Giselle HosgoodSchool of Veterinary Medicine, Murdoch University, Perth, Western Australia, Australia.
Mary ThompsonSchool of Veterinary Medicine, Murdoch University, Perth, Western Australia, Australia.
Flaminia CoiacettoSchool of Veterinary Medicine, Murdoch University, Perth, Western Australia, Australia.
Murdoch University · AU

Funding

Australian Companion Animal Health Foundation
6 · The paper itself

Abstract

backgroundGastroesophageal reflux and regurgitation occurs in brachycephalic dogs, but objective assessment is lacking.

objectivesQuantify reflux in brachycephalic dogs using an esophageal pH probe and determine the association with scored clinical observations. ANIMALS: Fifty-one brachycephalic dogs.

methodsCase review study. Signs of respiratory and gastrointestinal disease severity were graded based on owner assessment. An esophageal pH probe with 2 pH sensors was placed for 18-24 hours in brachycephalic dogs that presented for upper airway assessment. Proximal and distal reflux were indicated by detection of fluid with a pH ≤4. The median reflux per hour, percentage time pH ≤4, number of refluxes ≥5 minutes and longest reflux event for distal and proximal sensors were recorded. Association of preoperative respiratory and gastrointestinal grade, laryngeal collapse grade, and previous airway surgery with the distal percentage time pH ≤4 was examined using 1-way ANOVA.

resultsA total of 43 of 51 dogs (84%; 95% confidence interval 72-92) displayed abnormal reflux with a median (range) distal percentage time pH ≤4 of 6.4 (2.5-36.1). There was no significant association between the distal percentage time pH ≤4 and respiratory grade, gastrointestinal grade, laryngeal collapse grade, or previous upper airway surgery. CONCLUSIONS AND CLINICAL IMPORTANCE: The occurrence of reflux is not associated with owner-assessed preoperative respiratory and gastrointestinal grade, laryngeal collapse grade, and previous airway surgery. Esophageal pH measurement provides an objective assessment tool before and after surgery.

Indexed as

CraniosynostosesDog DiseasesGastroesophageal RefluxGastrointestinal DiseasesAnimalsDogsHydrogen-Ion ConcentrationVomitingbrachycephalicdigitrapperrefluxregurgitation

Identifiers

PMID35388526
PMCPMC9151495
OpenAlexW4226353416

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.