Evidence map›Paper›PMID 35388525›Full record

SynthesisPsycho-oncology2022

What is the prevalence of fear of cancer recurrence in cancer survivors and patients? A systematic review and individual participant data meta-analysis.

Yvonne L Luigjes-Huizer, Nina M Tauber, Gerry Humphris, Nadine A Kasparian, Wendy W T Lam, Sophie Lebel, Sébastien Simard, Allan Ben Smith, Robert Zachariae, Yati Afiyanti and 18 more

Open access · bronzeAbstract readMeta-AnalysisSystematic Review
In one paragraph

Synthesis in Psycho-oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 180 papers, 13 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
180citing papers in PubMed, 13 pooled it
27.4field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

180 citing papers in PubMed, 13 syntheses or guidelines pooled it, 280 citations in OpenAlex.

  1. How prevalent is fear of cancer recurrence beyond 5 years: a systematic review of validated assessments across tumour types.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2026
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  10. Ecosystem Barriers and Facilitators Linked to the Fear of Cancer Recurrence: An Umbrella Review.International journal of environmental research and public health · 2024
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120 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

28 authors at 20 institutions in 10 countries.

Yvonne L Luigjes-HuizerHelen Dowling Institute, Bilthoven, The Netherlands.ORCID 0000-0003-1611-3627
Nina M TauberUnit for Psychooncology and Health Psychology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0002-9334-5870
Gerry HumphrisSchool of Medicine, University of St Andrews, St Andrews, UK.ORCID 0000-0002-4601-8834
Nadine A KasparianCincinnati Children's Center for Heart Disease and Mental Health, Heart Institute and the Division of Behavioral Medicine & Clinical Psychology, Cincinnati Children's Hospital Medical Center and Department of Pediatrics, University of Cincinnati College of Medicine, Cincinnati, Ohio, USA.ORCID 0000-0001-8075-6817
Wendy W T LamDivision of Behavioural Sciences, School of Public Health, and LKS Faculty of Medicine Jockey Club Institute of Cancer Care, University of Hong Kong, Hong Kong, China.ORCID 0000-0003-2383-0149
Sophie LebelFaculty of Social Sciences, University of Ottawa, Ottawa, Ontario, Canada.ORCID 0000-0003-0019-8849
Sébastien SimardUniversité du Québec à Chicoutimi (UQAC), Centre Intersectoriel en santé durable, Québec, Québec, Canada.ORCID 0000-0001-7493-4672
Allan Ben SmithIngham Institute for Applied Medical Research and South West Sydney Clinical Campuses, UNSW, Sydney, New South Wales, Australia.ORCID 0000-0002-2496-7369
Robert ZachariaeUnit for Psychooncology and Health Psychology, Aarhus University and Aarhus University Hospital, Aarhus, Denmark.ORCID 0000-0001-9076-3068
Yati AfiyantiDepartment of Maternity and Women Health, Faculty of Nursing, Universitas Indonesia, Depok, Indonesia.ORCID 0000-0001-9382-6714
Katy J L BellSydney School of Public Health, Faculty of Medicine and Health, The University of Sydney, Sydney, New South Wales, Australia.ORCID 0000-0002-0137-3218
José A E CustersDepartment of Medical Psychology, Radboud University Medical Center, Radboud Institute for Health Sciences, Nijmegen, The Netherlands.ORCID 0000-0002-1573-6040
Niek J de WitJulius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands.ORCID 0000-0002-0273-8290
Peter L FisherDepartment of Psychological Sciences, University of Liverpool, Liverpool, UK.ORCID 0000-0002-7388-720X
Jacqueline GalicaDivision of Cancer Care and Epidemiology, Queen's University, Kingston, Ontario, Canada.ORCID 0000-0002-3072-2472
Sheila N GarlandDepartment of Psychology, Faculty of Science, Memorial University, St. John's, Newfoundland, Canada.ORCID 0000-0002-6119-318X
Charles W HelsperJulius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands.ORCID 0000-0002-3268-174X
Mette M JeppesenDepartment of Gynaecology and Obstetrics, Odense University Hospital, Odense, Denmark.ORCID 0000-0001-7390-5167
Jianlin LiuResearch Division, Institute of Mental Health, Singapore, Singapore.ORCID 0000-0003-0981-0643
Roxana MititeluFaculty of Medicine, McGill University, Montreal, Quebec, Canada.ORCID 0000-0002-4531-6012
Evelyn M MonninkhofJulius Centre for Health Sciences and Primary Care, University Medical Centre Utrecht, Utrecht, The Netherlands.ORCID 0000-0002-6641-7605
Lahiru RussellCentre for Quality and Patient Safety Research & Institute for Health Transformation, School of Nursing and Midwifery, Deakin University, Geelong, Victoria, Australia.ORCID 0000-0002-3806-0020
Josée SavardSchool of Psychology, Université Laval, CHU de Québec-Université Laval Research Center, Université Laval Cancer Research Centre, Quebec, Québec, Canada.ORCID 0000-0002-8052-1046
Anne E M SpeckensDepartment of Psychiatry, Radboud University Medical Centre, Nijmegen, The Netherlands.ORCID 0000-0001-5266-1554
Sanne J van HelmondtHelen Dowling Institute, Bilthoven, The Netherlands.ORCID 0000-0003-2812-2336
Sina VatandoustCollege of Medicine and Public Health, Flinders University, Bedford Park, South Australia, Australia.ORCID 0000-0002-4815-0994
Nicholas ZdenkowskiSchool of Medicine and Public Health, University of Newcastle, Newcastle, New South Wales, Australia.ORCID 0000-0001-8738-8463
Marije L van der LeeHelen Dowling Institute, Bilthoven, The Netherlands.ORCID 0000-0002-1316-7008
University Medical Center Utrecht · NLAarhus University Hospital · DKRadboud University Nijmegen · NLTilburg University · NLCincinnati Children's Hospital Medical Center · USDeakin University · AUFlinders University · AUHong Kong Jockey Club · CNInstitute of Mental Health · SGMcGill University · CAMemorial University of Newfoundland · CAOdense University Hospital · DKQueen's University · CAThe University of Sydney · AUUniversité du Québec à Chicoutimi · CAUniversité Laval · CAUniversity of Indonesia · IDUniversity of Liverpool · GBUniversity of Newcastle Australia · AUUniversity of Ottawa · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveCare for fear of cancer recurrence (FCR) is considered the most common unmet need among cancer survivors. Yet the prevalence of FCR and predisposing factors remain inconclusive. To support targeted care, we provide a comprehensive overview of the prevalence and severity of FCR among cancer survivors and patients, as measured using the short form of the validated Fear of Cancer Recurrence Inventory (FCRI-SF). We also report on associations between FCR and clinical and demographic characteristics.

methodsThis is a systematic review and individual participant data (IPD) meta-analysis on the prevalence of FCR. In the review, we included all studies that used the FCRI-SF with adult (≥18 years) cancer survivors and patients. Date of search: 7 February 2020. Risk of bias was assessed using the Joanna Briggs Institute critical appraisal tool.

resultsIPD were requested from 87 unique studies and provided for 46 studies comprising 11,226 participants from 13 countries. 9311 respondents were included for the main analyses. On the FCRI-SF (range 0-36), 58.8% of respondents scored ≥13, 45.1% scored ≥16 and 19.2% scored ≥22. FCR decreased with age and women reported more FCR than men. FCR was found across cancer types and continents and for all time periods since cancer diagnosis.

conclusionsFCR affects a considerable number of cancer survivors and patients. It is therefore important that healthcare providers discuss this issue with their patients and provide treatment when needed. Further research is needed to investigate how best to prevent and treat FCR and to identify other factors associated with FCR. The protocol was prospectively registered (PROSPERO CRD42020142185).

Indexed as

Cancer SurvivorsAdultFearFemaleHumansMaleNeoplasm Recurrence, LocalPhobic DisordersPrevalencecancercorrelatesfear of recurrenceoncologyprevalence

Identifiers

PMID35388525
PMCPMC9321869
OpenAlexW4224294941

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.