Evidence map›Paper›PMID 35388479›Full record

ArticleJournal of periodontal research2022

Regular dental visits, periodontitis, tooth loss, and atherosclerosis: The Ohasama study.

Sho Yamada, Takamasa Komiyama, Takashi Ohi, Takahisa Murakami, Yoshitada Miyoshi, Kosei Endo, Takako Hiratsuka, Azusa Hara, Michihiro Satoh, Yukako Tatsumi and 8 more

Open access · hybridAbstract read
In one paragraph

Article in Journal of periodontal research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
2.2field-weighted citation impact, top 13% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

  1. Review
  2. Observational
  3. Article
  4. Review
  5. Article
  6. Exosomal miR-155-5p promote the occurrence of carotid atherosclerosis.Journal of cellular and molecular medicine · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 5 institutions in 1 country.

Sho YamadaDivision of Aging and Geriatric Dentistry, Department of Rehabilitation Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.
Takamasa KomiyamaDivision of Aging and Geriatric Dentistry, Department of Rehabilitation Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.ORCID https://orcid.org/0000-0002-6778-1580
Takashi OhiDivision of Aging and Geriatric Dentistry, Department of Rehabilitation Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.
Takahisa MurakamiDivision of Aging and Geriatric Dentistry, Department of Rehabilitation Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.
Yoshitada MiyoshiDivision of Aging and Geriatric Dentistry, Department of Rehabilitation Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.
Kosei EndoDivision of Aging and Geriatric Dentistry, Department of Rehabilitation Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.
Takako HiratsukaDivision of Aging and Geriatric Dentistry, Department of Rehabilitation Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.
Azusa HaraDivision of Drug Development and Regulatory Science, Faculty of Pharmacy, Keio University, Tokyo, Japan.
Michihiro SatohDivision of Public Health, Hygiene and Epidemiology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Yukako TatsumiDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan.
Ryusuke InoueDepartment of Medical Information Technology Center, Tohoku University Hospital, Sendai, Japan.
Kei AsayamaDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan.
Masahiro KikuyaDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan.
Atsushi HozawaDepartment of Preventive Medicine and Epidemiology, Tohoku Medical Megabank Organization, Tohoku University, Sendai, Japan.
Hirohito MetokiDivision of Public Health, Hygiene and Epidemiology, Faculty of Medicine, Tohoku Medical and Pharmaceutical University, Sendai, Japan.
Yutaka ImaiTohoku Institute for Management of Blood Pressure, Sendai, Japan.
Takayoshi OhkuboDepartment of Hygiene and Public Health, Teikyo University School of Medicine, Tokyo, Japan.
Yoshinori HattoriDivision of Aging and Geriatric Dentistry, Department of Rehabilitation Dentistry, Tohoku University Graduate School of Dentistry, Sendai, Japan.
Tohoku University · JPTeikyo University · JPTohoku Medical and Pharmaceutical University · JPKeio University · JPTohoku University Hospital · JP

Funding

ACRO Incubation Grants of Teikyo UniversityGrant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 17H04126Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 17K15853Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 17K19930Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 18K09674Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 18K09904Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 18K17396Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 19H03908Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 19K10662Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 19K19325Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 19K19466Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 20K08612Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 21H04854Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 21K10452Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 21K10478Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 21K17313Grant-in-Aid for Scientific Research, Ministry of Education, Culture, Sports, Science, and Technology, Japan 21K19670Health Science Center Research GrantJapan Arteriosclerosis Prevention FundMinistry of Health, Labor, and Welfare, Japan 20FA1002Ministry of Health, Labor, and Welfare, Japan H29-Junkankitou-Ippan-003Research Support from Astellas Pharma Inc. and Takeda Pharmaceutical Co., Ltd.Scholarship donations from Chugai Pharmaceutical Co., Ltd., Daiichi Sankyo Co., Ltd.Takeda Science FoundationThe Academic Contributions from Pfizer Japan Inc.The Health Care Science Institute Research GrantThe internal research grants from Keio University
6 · The paper itself

Abstract

objectiveWe aimed to explore the association between regular dental visits and atherosclerosis and between periodontitis, number of remaining teeth, and atherosclerosis among community dwellers in Japan.

backgroundFew studies have examined the association between regular dental visits, periodontitis, tooth loss, and atherosclerosis in community dwellers in Japan.

methodsThe participants of this cross-sectional study included community dwellers aged ≥55 years and residing in Ohasama. Exposure variables were regular dental visits; periodontitis, defined as radiographic alveolar bone loss (BL); the Centers for Disease Control/American Academy of Periodontology (CDC/AAP) classification; and number of remaining teeth. The primary outcome was atherosclerosis, defined as maximum carotid intima-media thickness ≥1.1 mm or confirmation of atheromatous plaque.

resultsOf 602 participants, 117 had atherosclerosis. In the multivariate model, compared to those with regular dental visits, the odds ratio (OR) (95% confidence intervals [CIs]) of atherosclerosis among those with the absence of regular dental visits was 2.16 (1.03-4.49). Regarding BL-max, compared with those in the first quartile, ORs (95% CIs) of those in the second, third, and fourth quartiles were 1.15 (0.65-2.30), 0.65 (0.32-1.35), and 1.57 (0.81-3.01), respectively. Regarding CDC/AAP classification, compared to those with no or mild periodontitis, ORs (95% CIs) for those with moderate and severe periodontitis were 2.48 (0.61-10.1) and 4.26 (1.01-17.5), respectively. Regarding the number of remaining teeth, compared to those with ≥20 teeth, ORs (95%CIs) for those with 10-19 and 1-9 teeth were 1.77 (1.004-3.12) and 0.96 (0.52-1.80), respectively.

conclusionThe absence of regular dental visits and presence of periodontitis are associated with atherosclerosis among community dwellers in Japan.

Indexed as

AtherosclerosisPeriodontitisTooth LossCarotid Intima-Media ThicknessCross-Sectional StudiesHumansalveolar bone lossatherosclerosisepidemiologyperiodontitisregular dental visittooth loss

Identifiers

PMID35388479
PMCPMC9321748
OpenAlexW4224302387

What OpenQuestion holds

Textmetadata
LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.