Evidence map›Paper›PMID 35388304›Full record

ReviewEvidence-based complementary and alternative medicine : eCAM2022

Biogenic Phytochemicals Modulating Obesity: From Molecular Mechanism to Preventive and Therapeutic Approaches.

Vikram Kumar, Desh Deepak Singh, Sudarshan Singh Lakhawat, Nusrath Yasmeen, Aishwarya Pandey, Rajeev K Singla

Open access · hybridAbstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in Evidence-based complementary and alternative medicine : eCAM, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
9.7field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 57 citations in OpenAlex.

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  15. A Review of the Potential Health Benefits ofPlants (Basel, Switzerland) · 2023
    Review
  16. International journal of molecular sciences · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 2 countries.

Vikram KumarAmity Institute of Biotechnology, Amity University Rajasthan, Jaipur 303002, Rajasthan, India.ORCID https://orcid.org/0000-0002-9994-8904
Desh Deepak SinghAmity Institute of Biotechnology, Amity University Rajasthan, Jaipur 303002, Rajasthan, India.
Sudarshan Singh LakhawatAmity Institute of Biotechnology, Amity University Rajasthan, Jaipur 303002, Rajasthan, India.
Nusrath YasmeenAmity Institute of Biotechnology, Amity University Rajasthan, Jaipur 303002, Rajasthan, India.ORCID https://orcid.org/0000-0002-9913-5620
Aishwarya PandeyINRS, Eau Terre Environnement Research Centre, Québec, QC, Canada.
Rajeev K SinglaInstitutes for Systems Genetics, Frontiers Science Center for Disease-Related Molecular Network, West China Hospital, Sichuan University, Chengdu 610041, Sichuan, China.ORCID https://orcid.org/0000-0002-3353-7897
Institut National de la Recherche Scientifique · CASichuan University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The incidence of obesity and over bodyweight is emerging as a major health concern. Obesity is a complex metabolic disease with multiple pathophysiological clinical conditions as comorbidities are associated with obesity such as diabetes, hypertension, cardiovascular disorders, sleep apnea, osteoarthritis, some cancers, and inflammation-based clinical conditions. In obese individuals, adipocyte cells increased the expression of leptin, angiotensin, adipocytokines, plasminogen activators, and C-reactive protein. Currently, options for treatment and lifestyle behaviors interventions are limited, and keeping a healthy lifestyle is challenging. Various types of phytochemicals have been investigated for antiobesity potential. Here, we discuss pathophysiology and signaling pathways in obesity, epigenetic regulations, regulatory mechanism, functional ingredients in natural antiobesity products, and therapeutic application of phytochemicals in obesity.

Identifiers

PMID35388304
PMCPMC8977300
OpenAlexW4220939572

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.