Evidence map›Paper›PMID 35388295›Full record

ArticleFrontiers in endocrinology2022

Computed Tomography-Based Machine Learning Differentiates Adrenal Pheochromocytoma From Lipid-Poor Adenoma.

Haipeng Liu, Xiao Guan, Beibei Xu, Feiyue Zeng, Changyong Chen, Hong Ling Yin, Xiaoping Yi, Yousong Peng, Bihong T Chen

Abstract read
In one paragraph

Article in Frontiers in endocrinology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Article
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  9. Review
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  12. Artificial intelligence in endocrinology: a comprehensive review.Journal of endocrinological investigation · 2024
    Review
  13. Article
  14. World journal of surgical oncology · 2023
    Article
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  17. Review
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  20. A longitudinal study of dual-energy X-ray absorptiometry status in menopausal women with adrenal tumors.Romanian journal of morphology and embryology = Revue roumaine de morphologie et embryologie
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Haipeng LiuDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, China.
Xiao GuanNational Clinical Research Center for Geriatric Disorders, Xiangya Hospital, Changsha, China.
Beibei XuCollege of Biology, Hunan University, Changsha, China.
Feiyue ZengDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, China.
Changyong ChenDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, China.
Hong Ling YinDepartment of Pathology, Xiangya Hospital, Central South University, Changsha, China.
Xiaoping YiDepartment of Radiology, Xiangya Hospital, Central South University, Changsha, China.
Yousong PengCollege of Biology, Hunan University, Changsha, China.
Bihong T ChenDepartment of Diagnostic Radiology, City of Hope National Medical Center, Los Angeles, CA, United States.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objectives: To assess the accuracy of computed tomography (CT)-based machine learning models for differentiating subclinical pheochromocytoma (sPHEO) from lipid-poor adenoma (LPA) in patients with adrenal incidentalomas. Patients and Methods: The study included 188 tumors in the 183 patients with LPA and 92 tumors in 86 patients with sPHEO. Pre-enhanced CT imaging features of the tumors were evaluated. Machine learning prediction models and scoring systems for differentiating sPHEO from LPA were built using logistic regression (LR), support vector machine (SVM) and random forest (RF) approaches. Results: The LR model performed better than other models. The LR model (M1) including three CT features: CT Conclusions: Our results indicated the potential of using a non-invasive imaging method such as CT-based machine learning models and scoring systems for predicting histology of adrenal incidentalomas. This approach may assist the diagnosis and personalized care of patients with adrenal tumors.

Indexed as

AdenomaAdrenal Gland NeoplasmsPheochromocytomaHumansLipidsMachine LearningRetrospective StudiesTomography, X-Ray ComputedLipidsadrenal incidentalomacomputed tomographylipid-poor adenomalogistic regressionmachine learningsubclinical pheochromocytoma

Identifiers

PMID35388295
PMCPMC8977471

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.