ArticleNature2022
Compartmentalized metabolism supports midgestation mammalian development.
Open access · hybridAbstract read
In one paragraph
Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 85 papers.
0numbers the graph read from it
0cells of the map it votes in
85citing papers in PubMed
40.0field-weighted citation impact, top 1% of its field
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
85 citing papers in PubMed, 111 citations in OpenAlex.
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- Placental nicotinamide adenine dinucleotide modulates the timing of labor.Science (New York, N.Y.) · 2026Article
- Placenta-Derived Extracellular Vesicles (pdEVs): Key Mediators That Affect the Metabolic Health of Offspring in Early Nutritional Environments.Biomolecules · 2026Review
- Research advances of copper homeostasis and cuproptosis in orthopedic diseases.Cell death discovery · 2026Review
- Biomimetic phycocyanin lipid-based nanoparticles ameliorate placental dysfunction and restore angiogenic balance in a pre-eclampsia model.Journal of nanobiotechnology · 2026Article
- Nitrogen metabolism profiling reveals cell state-specific pyrimidine synthesis pathway choice.Nature metabolism · 2026Article
- A Stable Isotope Tracing Primer for the Mass Spectrometrist.Annual review of analytical chemistry (Palo Alto, Calif.) · 2026Review
- Metabolomics Highlights Reduced Glutamate and Acetylcarnitine in the Amniotic Fluid of Cytomegalovirus-Infected Pregnant Women.Journal of proteome research · 2026Article
- Dynamics of the Mammalian Placental Metabolome in Placentogenesis and Embryonic Development.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Factor VIII restores bone parameters and modulates muscle proteo-metabolome in Factor VIII knockout male mice.Bone research · 2026Article
- Placental Steroid Hormones in Preeclampsia: Multilayered Regulation of Endocrine Pathogenesis.Endocrine reviews · 2026Review
- Metabolic Reprogramming Driven by Trophoblasts and Decidual XCR1Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Metabolic control of feto-placental development and pregnancy outcomes.Nature reviews. Endocrinology · 2026Review
- NADCell reports · 2026Article
- Effect of EGR1/LIPT1 regulatory axis on cuproptosis in chromophobe renal cell carcinoma.Briefings in functional genomics · 2026Article
- Targeting multiple genetic defects of mitochondrial diseases with a single bacterial lipoate protein ligase.Science advances · 2025Article
- Vegetable Leaf Fermentation Improves Nutritional Quality of Sheep Feed, Enhancing Growth Performance and Intestinal Health.Animals : an open access journal from MDPI · 2025Article
25 more citing papers are in PubMed but not listed here.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
26 authors at 3 institutions in 2 countries.
Ashley SolmonsonChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Brandon FaubertChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0002-2886-886X
Wen GuChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0002-3003-8945
Aparna RaoChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Mitzy A CowdinDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0003-0549-2473
Ivan Menendez-MontesDivision of Cardiology, Department of Internal Medicine, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0001-5252-9502
Sherwin KelekarChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Thomas J RogersChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Chunxiao PanChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Gerardo GuevaraChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Amy TarangeloChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Lauren G ZachariasChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Misty S Martin-SandovalChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Duyen DoChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Panayotis PachnisChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Dennis DumesnilChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Thomas P MathewsChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Alpaslan TasdoganChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
An PhamDepartment of Pediatrics, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Ling CaiChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Zhiyu ZhaoChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0001-6308-6997
Min NiChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Ondine CleaverDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
Hesham A SadekDepartment of Molecular Biology, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0002-4745-366X
Sean J MorrisonChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA.ORCID http://orcid.org/0000-0003-1587-8329
Ralph J DeBerardinisChildren's Medical Center Research Institute, University of Texas Southwestern Medical Center, Dallas, TX, USA. ralph.deberardinis@utsouthwestern.edu.ORCID http://orcid.org/0000-0002-2705-7432
Children's Medical Center · USThe University of Texas Southwestern Medical Center · USSouthwestern Medical Center · US
Funding
Metabolic Regulators of Tumor Growth and ProgressionR35CA220449 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI RALPH J DEBERARDINIS · 2017 to 2026
$9.4MIdentifying factors regulating cancer metabolism in vivoR00CA237724 · NCI · UNIVERSITY OF CHICAGO · PI FAUBERT, BRANDON · 2022 to 2024
$667kTargeting a Kynurenine-Driven Autocrine Loop to Block Triple-Negative Breast Cancer MetastasisK00CA212230 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI ROGERS, THOMAS J · 2017 to 2020
$326kInvestigating the Role of Metabolic Reprogramming in Cancer Cell Death SensitivityK00CA234650 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI TARANGELO, AMY · 2020 to 2022
$278kIdentifying factors regulating cancer metabolism in vivoK99CA237724 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI FAUBERT, BRANDON · 2020 to 2021
$219kThe consequences of human inborn errors in mitochondrial lipoic acid metabolismF32HD096786 · NICHD · UT SOUTHWESTERN MEDICAL CENTER · PI SOLMONSON, ASHLEY D · 2018 to 2020
$197kThe Role of Glucose-6-Phosphatase in Hepatocellular CarcinomaF30CA254150 · NCI · UT SOUTHWESTERN MEDICAL CENTER · PI KELEKAR, SHERWIN · 2021 to 2024
$139kNCI NIH HHS F30 CA254150NCI NIH HHS K00 CA212230NCI NIH HHS K00 CA234650NCI NIH HHS K99 CA237724NCI NIH HHS R00 CA237724NCI NIH HHS R35 CA220449NCIPC CDC HHS R35 CA22044901NICHD NIH HHS F32 HD096786
Abstract
Mammalian embryogenesis requires rapid growth and proper metabolic regulation
Indexed as
Citric Acid CycleFetal DevelopmentMetabolomicsPlacentaAnimalsEmbryo, MammalianFemaleGlucoseMammalsMicePregnancyGlucose
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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.