Evidence map›Paper›PMID 35388124›Full record

ArticleScientific reports2022

Differentiating solitary brain metastases from glioblastoma by radiomics features derived from MRI and 18F-FDG-PET and the combined application of multiple models.

Xu Cao, Duo Tan, Zhi Liu, Meng Liao, Yubo Kan, Rui Yao, Liqiang Zhang, Lisha Nie, Ruikun Liao, Shanxiong Chen and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed.

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  13. Towards updated understanding of brain metastasis.American journal of cancer research · 2022
    Review
  14. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Xu Cao *School of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Duo Tan *College of Computer & Information Science, Southwest University, Chongqing, China.
Zhi Liu *Department of Radiology, Chongqing Traditional Chinese Medicine Hospital, Chongqing, China.
Meng LiaoSchool of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Yubo KanSchool of Medical and Life Sciences, Chengdu University of Traditional Chinese Medicine, Chengdu, China.
Rui YaoCollege of Computer & Information Science, Southwest University, Chongqing, China.
Liqiang ZhangDepartment of Radiology, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Lisha NieGE Healthcare, MR Research China, Beijing, China.
Ruikun LiaoDepartment of Radiology, Chongqing General Hospital, Chongqing, China. 330357551@qq.com.
Shanxiong ChenCollege of Computer & Information Science, Southwest University, Chongqing, China. csxpml@163.com.
Mingguo XieDepartment of Radiology, Hospital of Chengdu University of Traditional Chinese Medicine, Chengdu, China. 767030837@qq.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to explore the ability of radiomics derived from both MRI and 18F-fluorodeoxyglucose positron emission tomography (18F-FDG-PET) images to differentiate glioblastoma (GBM) from solitary brain metastases (SBM) and to investigate the combined application of multiple models. The imaging data of 100 patients with brain tumours (50 GBMs and 50 SBMs) were retrospectively analysed. Three model sets were built on MRI, 18F-FDG-PET, and MRI combined with 18F-FDG-PET using five feature selection methods and five classification algorithms. The model set with the highest average AUC value was selected, in which some models were selected and divided into Groups A, B, and C. Individual and joint voting predictions were performed in each group for the entire data. The model set based on MRI combined with 18F-FDG-PET had the highest average AUC compared with isolated MRI or 18F-FDG-PET. Joint voting prediction showed better performance than the individual prediction when all models reached an agreement. In conclusion, radiomics derived from MRI and 18F-FDG-PET could help differentiate GBM from SBM preoperatively. The combined application of multiple models can provide greater benefits.

Indexed as

Brain NeoplasmsGlioblastomaFluorodeoxyglucose F18HumansMagnetic Resonance ImagingPositron-Emission TomographyPositron Emission Tomography Computed TomographyRadiopharmaceuticalsRetrospective StudiesFluorodeoxyglucose F18Radiopharmaceuticals

Identifiers

PMID35388124
PMCPMC8986767

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.