Evidence map›Paper›PMID 35388088›Full record

ArticleScientific reports2022

Glucose and unstructured physical activity coupling during sleep and wake in young adults with type 1 diabetes.

Stephanie Griggs, Eric Barbato, Estefania Hernandez, Devansh Gupta, Seunghee Margevicius, Margaret Grey, Ronald L Hickman

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Stephanie GriggsRuth M. Anderson Endowed Professor of Nursing and Associate Dean for Research, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, 44106, USA. Stephanie.griggs@case.edu.ORCID 0000-0001-9901-3853
Eric BarbatoDepartment of Genetics and Genome Sciences, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.ORCID 0000-0001-8132-0679
Estefania HernandezDepartment of Anthropology, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, 44106, USA.ORCID 0000-0002-8925-911X
Devansh GuptaRuth M. Anderson Endowed Professor of Nursing and Associate Dean for Research, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, 44106, USA.ORCID 0000-0001-9180-9611
Seunghee MargeviciusDepartment of Population and Quantitative Health Sciences, Case Comprehensive Cancer Center, School of Medicine, Case Western Reserve University, Cleveland, OH, 44106, USA.ORCID 0000-0001-5663-8319
Margaret GreyAnnie Goodrich Professor of Nursing and Professor of Pediatrics, School of Nursing and School of Medicine, Yale University, West Haven, CT, 06477, USA.ORCID 0000-0003-2473-8088
Ronald L HickmanRuth M. Anderson Endowed Professor of Nursing and Associate Dean for Research, Frances Payne Bolton School of Nursing, Case Western Reserve University, Cleveland, OH, 44106, USA.ORCID 0000-0002-3720-2955
Case Western Reserve University · USYale University · US

Funding

Research Training: Self and Family ManagementT32NR008346 · NINR · YALE UNIVERSITY · PI GREY, MARGARET · 2003 to 2018
$4.7M
Sleep, Glycemia, and Self-Management in Young Adults with Type 1 Diabetes MellitusR00NR018886 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI GRIGGS, STEPHANIE ALISHA · 2021 to 2023
$729k
Sleep, Glycemia, and Self-Management in Young Adults with Type 1 Diabetes MellitusK99NR018886 · NINR · CASE WESTERN RESERVE UNIVERSITY · PI GRIGGS, STEPHANIE ALISHA · 2020 to 2020
$93k
NINR NIH HHS K99 NR018886NINR NIH HHS R00 NR018886NINR NIH HHS R00NR018886NINR NIH HHS T32NR0008346NINR NIH HHS T32 NR008346
6 · The paper itself

Abstract

Glucose variations have a bidirectional relationship with the sleep/wake and circadian systems in type 1 diabetes (T1D); however, the mechanisms remain unclear. The aim of this study was to describe the coupling between glucose and unstructured physical activity over 168 h in young adults with T1D. We hypothesized that there would be differences in sleep and wake characteristics and circadian variations. Glucose was measured with a continuous glucose monitoring device every 5 min and activity with a non-dominant wrist-worn actigraph in 30-s epochs over 6-14 days. There was substantial glucose and unstructured physical activity coupling during sleep and wake, along with circadian variation based on the wavelet coherence analysis. The extent to which glucose fluctuations result in disrupted sleep over longer than one week should be examined considering the harmful effects on achieving glycemic targets. Further studies are needed to delineate the respective roles of glucose production and utilization and the potential for improved meal and insulin timing to optimize glucose and sleep in this population reliant on exogenous insulin.

Indexed as

Diabetes Mellitus, Type 1Blood GlucoseBlood Glucose Self-MonitoringCircadian RhythmExerciseGlucoseHumansInsulinSleepYoung AdultBlood GlucoseGlucoseInsulin

Identifiers

PMID35388088
PMCPMC8986774
OpenAlexW4223641736

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.