Evidence map›Paper›PMID 35387702›Full record

ArticleInfection control and hospital epidemiology2023

A mixed-methods evaluation on the efficacy and perceptions of needleless connector disinfectants.

Scott C Roberts, Curtis A Hendrix, Lauren M Edwards, Richard S Feinn, Richard A Martinello, Thomas S Murray

Open access · hybridAbstract read
In one paragraph

Article in Infection control and hospital epidemiology, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 9 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Scott C RobertsDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.ORCID 0000-0001-7348-6716
Curtis A HendrixDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.ORCID 0000-0001-5946-8335
Lauren M EdwardsQuality & Safety, Yale New Haven Children's Hospital, New Haven, Connecticut.
Richard S FeinnDepartment of Medical Sciences, Frank H. Netter MD School of Medicine, Quinnipiac University North Haven, North Haven, Connecticut.
Richard A MartinelloDepartment of Internal Medicine, Yale School of Medicine, New Haven, Connecticut.ORCID 0000-0002-0355-9200
Thomas S MurrayDepartment of Infection Prevention, Yale New Haven Health, New Haven, Connecticut.ORCID 0000-0002-6829-7213
Yale University · USQuinnipiac University · USYale New Haven Hospital · US

Funding

Yale Clinical and Translational Science Award (U Component)UL1TR001863 · NCATS · YALE UNIVERSITY · PI John H. Krystal, LUCILA OHNO-MACHADO · 2016 to 2026
$102.9M
NCATS NIH HHS UL1 TR001863
6 · The paper itself

Abstract

objectiveOptimizing needleless connector hub disinfection practice is a key strategy in central-line-associated bloodstream infection (CLABSI) prevention. In this mixed-methods evaluation, 3 products with varying scrub times were tested for experimental disinfection followed by a qualitative nursing assessment of each.

methodsNeedleless connectors were inoculated with varying concentrations of

resultsAll products reduced overall bacterial burden when compared to sterile water controls, however the IPA and CHG/IPA wipes were superior to the IPA caps when product efficacy was compared. Nursing staff noted improved compliance with CHG/IPA wipes compared with the IPA wipes and the IPA caps, with many preferring the lesser scrub and dry times required for disinfection.

conclusionAchieving adequate bacterial disinfection of needleless connectors while maximizing healthcare staff compliance with scrub and dry times may be best achieved with a combination CHG/IPA wipe.

Indexed as

Cross InfectionDisinfectants2-PropanolCatheters, IndwellingChlorhexidineDisinfectionHumans2-PropanolChlorhexidineDisinfectants

Identifiers

PMID35387702
PMCPMC9929708
OpenAlexW4225244070

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.