Evidence map›Paper›PMID 35387676›Full record

ArticleBMC health services research2022

Improving safety and efficacy with pharmacist medication reconciliation in orthopedic joint surgery within an enhanced recovery after surgery program.

Xiaoying Zheng, Lei Xiao, Ying Li, Feng Qiu, Wei Huang, Xinyu Li

Abstract read
In one paragraph

Article in BMC health services research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaoying Zheng *Department of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Yuzhong District, 1 Youyi Rd, Chongqing, China.
Lei Xiao *Department of Pharmacy, Chongqing Health Center for Women and Children, Chongqing, China.
Ying LiDepartment of Orthopedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Feng QiuDepartment of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Yuzhong District, 1 Youyi Rd, Chongqing, China.
Wei HuangDepartment of Orthopedic Surgery, The First Affiliated Hospital of Chongqing Medical University, Chongqing, China.
Xinyu LiDepartment of Pharmacy, The First Affiliated Hospital of Chongqing Medical University, Yuzhong District, 1 Youyi Rd, Chongqing, China. ariel_lee1983@icloud.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo investigate the impact of medication reconciliation (MR), through avoidance of unintentional medication discrepancies, on enhanced recovery after surgery programs designed for older patients undergoing orthopedic joint surgery. 

methodOur study was divided into two phases. In the first phase, MR was performed for elderly patients undergoing orthopedic joint surgery. Types of medication discrepancies and their potential risks were analyzed. In the second phase, a controlled study was conducted in a subgroup of patients diagnosed with periprosthetic joint infection (PJI) and who were scheduled for two-stage revision. The primary goal was to investigate the impact of MR on length of stay for the first stage. The secondary goal was to investigate the time between the first admission and the reimplantation of a new prosthesis, the number of readmissions within 30 days, hospitalization cost.

resultsA total of 506 medication discrepancies were identified in the included 260 patients. Intolerance had the highest incidence (n = 131, 25.7%). The Bayliff tool showed that 71.9% were assessed as level 2 risk, and 10.3% had a life-threatening risk. For patients with PJI, MR reduced the average length of stay in the first stage (16.3 days vs. 20.7 days, P = 0.03) and shortened the time (57.3 days vs. 70.5 days, P = 0.002) between the first admission and the reimplantation of a new prosthesis. The average cost of hospital stay ($8589.6 vs. $10,422.6, P = 0.021), antibiotics ($1052.2 vs. $1484.7, P = 0.032) and other medications ($691.5 vs. $1237.6, P = 0.014) per patient at our hospital were significantly decreased. Notably, significant improvements in patient satisfaction were seen in participants in the MR group.

conclusionThrough MR by clinical pharmacists, medication discrepancies within the orthopedic ERAS program could be identified. For patients with periprosthetic joint infection, better patient satisfaction and clinical and economical outcomes can be achieved with this method.

Indexed as

Enhanced Recovery After SurgeryProsthesis-Related InfectionsAgedHumansMedication ErrorsMedication ReconciliationPatient AdmissionPharmacistsEnhanced recovery after surgeryMedication discrepancyMedication reconciliationPeriprosthetic joint infection

Identifiers

PMID35387676
PMCPMC8985260

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.