ArticleWorld journal of surgical oncology2022
Surgical site infection after laparoscopic resection of colorectal cancer is associated with compromised long-term oncological outcome.
Article in World journal of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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16 citing papers in PubMed, 18 citations in OpenAlex.
- Impact of Postoperative Infectious Complications on Long-Term Survival After Curative Resection for Colorectal Cancer: A Multicenter Study in the Minimally Invasive Era.Annals of gastroenterological surgery · 2026Article
- The Impact of Postoperative Complications After Colon Cancer Surgery on Locoregional Recurrence: A Population-Based Dutch Cohort Study.Annals of surgical oncology · 2026Article
- Combined prophylactic negative-pressure wound therapy and preoperative oral antibiotics reduce perineal wound complications after abdominoperineal resection.Surgery today · 2026Article
- Convergent immune dysregulation in sepsis and colorectal cancer highlights plasma cells and identifies shared candidate genes.Discover oncology · 2026Article
- Prophylactic negative pressure wound therapy with Prevena™ to prevent perineal surgical site infection.Surgery today · 2025Article
- Light-based therapy of infected wounds: a review of dose considerations for photodynamic microbial inactivation and photobiomodulation.Journal of biomedical optics · 2025Review
- Prospective study on surgical site infections in major oncologic resections.Bioinformation · 2025Article
- Prognostic Value of Immune Scoring System for Colorectal Cancer Patients with Peritoneal Metastasis.Medicina (Kaunas, Lithuania) · 2024Article
- Effect of postoperative complications on 5-year survival following laparoscopic surgery for resectable colorectal cancer: a retrospective study.International journal of colorectal disease · 2024Article
- A retrospective study examining the association between polypharmacy and complications after laparoscopic surgery for colorectal cancer.Journal of pharmaceutical health care and sciences · 2024Article
- Article
- Incidence of surgical site infection in minimally invasive colorectal surgery.World journal of gastrointestinal surgery · 2024Article
- The Impact of Different Types of Complications on Long-Term Survival After Total Gastrectomy for Gastric Cancer.Journal of gastric cancer · 2023Article
- Postoperative infectious complications have a negative oncological impact in patients after stent placement with malignant large bowel obstruction.International journal of colorectal disease · 2023Article
- Traditional Chinese medicine as a novel therapy for colorectal cancer by modulating intestinal flora.Journal of Cancer · 2023Article
- Effects of wound infection on prognosis after laparoscopic abdominoperineal resection of rectal cancer.Frontiers in oncology · 2022Article
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Authors and funding
11 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWe evaluated the influence of infectious complications, particularly surgical site infection (SSI), on long-term oncological results after elective laparoscopic resection of colorectal cancer.
methodsA total of 199 patients who underwent laparoscopic elective resection with negative resection margins for stage I-III colorectal cancer were retrospectively examined. The postoperative course was recorded based on hospital records, and cancer relapse was diagnosed based on radiological or pathological findings under a standardized follow-up program. The severity of complications was graded using Clavien-Dindo (CD) classification.
resultsSSI was found in 25 patients (12.6%), with 12 (6.0%) showing anastomotic leak. The postoperative relapse-free survival (RFS) rate was significantly lower in patients with SSI (49.2%) than in patients without SSI (87.2%, P<0.001). Differences in RFS were found after both colectomy and rectal resection (P<0.001 and P<0.001, respectively). RFS did not differ between patients who had major SSI CD (grade III) and those who had minor SSI CD (grades I or II). Multivariate Cox regression analysis identified the occurrence of SSI and pathological stage as independent co-factors for RFS (P<0.001 and P=0.003).
conclusionThese results suggest that postoperative SSI compromises long-term oncological results after laparoscopic colorectal resection. Further improvements in surgical technique and refinements in perioperative care may improve long-term oncological results.
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