Evidence map›Paper›PMID 35387664›Full record

ArticleBMC veterinary research2022

First glanders cases detected in Nepal underscore the need for surveillance and border controls.

Koirala P, Maharjan M, Manandhar S, Pandey Kr, Deshayes T, Wang G, Valvano Ma, Laroucau K

Open access · goldAbstract readCase Reports
In one paragraph

Article in BMC veterinary research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.1field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 8 citations in OpenAlex.

  1. Review
  2. Review
  3. Identification of persistent clusters and temporal trends of glanders in horses throughout Brazil.Brazilian journal of microbiology : [publication of the Brazilian Society for Microbiology] · 2025
    Article
  4. Development and validation of a chemiluminescent western blot assay for glanders (Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc · 2024
    Article
  5. Article
  6. Sequence-based detection and typing procedures forFrontiers in veterinary science · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

Koirala PCentral Veterinary Laboratory, Kathmandu, Nepal. paggya2000@gmail.com.
Maharjan MCentral Veterinary Laboratory, Kathmandu, Nepal.
Manandhar SCentral Veterinary Laboratory, Kathmandu, Nepal.
Pandey KrVeterinary Laboratory, Surkhet, Nepal.
Deshayes TANSES, Laboratory for Animal Health, Bacterial Zoonosis Unit, European and OIE Reference Laboratory for Glanders, Paris-Est University, Maisons-Alfort, France.
Wang GWellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.
Valvano MaWellcome-Wolfson Institute for Experimental Medicine, Queen's University Belfast, Belfast, UK.
Laroucau KANSES, Laboratory for Animal Health, Bacterial Zoonosis Unit, European and OIE Reference Laboratory for Glanders, Paris-Est University, Maisons-Alfort, France. karine.laroucau@anses.fr.
Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail · FRQueen's University Belfast · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlanders is a transmissible zoonotic disease caused by Burkholderia mallei that infects equids and humans. No glanders cases in equids were reported so far in Nepal. CASE PRESENTATION: Following suspected glanders in animals with clinical signs in different regions in Nepal, serum samples were tested by CFT, ELISA and Luminex® tests. Two horses and a mule tested positive for glanders by all tests, while two other equids only tested positive by ELISA and Luminex®. Analysis of swabs and pus samples by a PCR system targeting B. mallei confirmed the presence of the bacterium in the samples collected from the 3 equids that yielded positive results in all serological tests. Genotyping of the three PCR positive samples with a SNP-based method identified a genotype closely related to the B. mallei strains circulating in India.

conclusionConfirmation of glanders cases underscores the need of implementing a surveillance program in Nepal and a strict control of the animal movement across the borders.

Indexed as

Burkholderia malleiGlandersHorse DiseasesAnimalsEnzyme-Linked Immunosorbent AssayEquidaeHorsesNepalBurkholderia malleiEquidsIndia

Identifiers

PMID35387664
PMCPMC8985341
OpenAlexW4223509897

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.