Evidence map›Paper›PMID 35387660›Full record

ArticleJournal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance2022

Cardiovascular magnetic resonance characterization of rheumatic mitral stenosis: findings from three worldwide endemic zones.

Mahesh K Vidula, Ziqian Xu, Yuanwei Xu, Abdullah Alturki, Bhavana N Reddy, Prayaag Kini, Angel L Alberto-Delgado, Ron Jacob, Tiffany Chen, Victor A Ferrari and 4 more

Open access · goldAbstract read
In one paragraph

Article in Journal of cardiovascular magnetic resonance : official journal of the Society for Cardiovascular Magnetic Resonance, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.8field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 4 citations in OpenAlex.

  1. Article
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  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 6 institutions in 4 countries.

Mahesh K VidulaDivision of Cardiovascular Medicine, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.ORCID 0000-0002-7701-8757
Ziqian XuDepartment of Radiology, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Yuanwei XuDivision of Cardiology, Department of Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Abdullah AlturkiDivision of Cardiothoracic Imaging, Department of Radiology, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Bhavana N ReddyDepartment of Radiology, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, Karnataka, India.
Prayaag KiniDepartment of Cardiology, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, Karnataka, India.
Angel L Alberto-DelgadoCentral Army Hospital of the National Secretary of Defense, Mexico City, Mexico.
Ron JacobDivision of Cardiovascular Medicine, Lancaster General Hospital, Lancaster, PA, USA.
Tiffany ChenDivision of Cardiovascular Medicine, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Victor A FerrariDivision of Cardiovascular Medicine, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA.
Lilia M Sierra-GalanDivision of Cardiology, American British Cowdray Medical Center, Mexico City, Mexico.
Yucheng ChenDivision of Cardiology, Department of Medicine, West China Hospital, Sichuan University, Chengdu, Sichuan, China.
Sanjaya ViswamitraDepartment of Radiology, Sri Sathya Sai Institute of Higher Medical Sciences, Bangalore, Karnataka, India.
Yuchi HanDivision of Cardiovascular Medicine, Department of Medicine, Hospital of the University of Pennsylvania, Philadelphia, PA, USA. yuchi.han@osumc.edu.
Hospital of the University of Pennsylvania · USSichuan University · CNSri Sathya Sai Institute of Higher Medical Sciences · INCentro Médico ABC · MXHospital Central Militar · MXLancaster General Hospital · US

Funding

Imaging-based Indentification of Premature Ventricular Contraction-mediatedR01HL148103 · NHLBI · UNIVERSITY OF PENNSYLVANIA · PI HAN, YUCHI · 2020 to 2025
$2.8M
NHLBI NIH HHS R01 HL148103
6 · The paper itself

Abstract

backgroundCardiac remodeling in rheumatic mitral stenosis (MS) is complex and incompletely understood. The objective of this study was to evaluate cardiac structural and functional changes in a cohort of patients with rheumatic MS using cardiovascular magnetic resonance (CMR).

methodsThis retrospective study included 40 patients with rheumatic MS, consisting of 19 patients from India, 15 patients from China, and 6 patients from Mexico (median (interquartile range (IQR)) age: 45 years (34-55); 75% women). Twenty patients were included in the control group. CMR variables pertaining to morphology and function were collected. Late gadolinium enhancement (LGE) sequences were acquired for tissue characterization. Statistical analyses were performed using the Kruskal-Wallis test and the chi-square test.

resultsCompared to the control group, patients with MS had lower left ventricular (LV) ejection fraction (51% (42%-55%) vs 60% (57%-65%), p < 0.001), lower right ventricular (RV) ejection fraction (44% (40%-52%) vs 64% (59%-67%), p < 0.001), higher RV end-diastolic volume (72 (58-87) mL/m

conclusionOur findings demonstrated that biventricular dysfunction, right and left atrial remodeling, and LGE at the RV insertion sites are underappreciated in contemporary rheumatic MS. Further studies are needed to elucidate the prognostic implications of these findings.

Indexed as

Mitral Valve StenosisContrast MediaFemaleGadoliniumHumansMagnetic Resonance Imaging, CineMagnetic Resonance SpectroscopyMaleMiddle AgedPredictive Value of TestsRetrospective StudiesStroke VolumeVentricular Function, LeftVentricular RemodelingContrast MediaGadoliniumCardiac remodelingCardiovascular magnetic resonanceRheumatic mitral stenosis

Identifiers

PMID35387660
PMCPMC8988335
OpenAlexW4223584287

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.