ArticleWorld journal of surgical oncology2022
Cement leakage in percutaneous vertebroplasty for spinal metastases: a retrospective study of risk factors and clinical outcomes.
Article in World journal of surgical oncology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.
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Who cites it
15 citing papers in PubMed, 1 synthesis or guideline pooled it, 18 citations in OpenAlex.
- The role of minimally invasive surgery within a multidisciplinary approach for patients with metastatic spine disease over a decade: A systematic review.Neuro-oncology · 2024Pooled it
- Prognostic analysis of percutaneous vertebroplasty (PVP) combined withWorld journal of surgical oncology · 2023Trial
- Complications of vertebral augmentation in metastatic spinal fractures: a systematic review of multiple study designs.Journal of bone oncology · 2026Review
- Efficacy of polymethyl methacrylate combined with calcium phosphate cement in percutaneous vertebroplasty for postmenopausal women with osteoporotic thoracolumbar compression fractures.Journal of orthopaedic surgery and research · 2026Article
- Development and validation of a nomogram model for predicting bone cement leakage during vertebroplasty.BMC surgery · 2026Article
- Upper thoracic T1 and T2 percutaneous vertebroplasty: a review of 10 years of experience.European radiology · 2026Article
- Risk factors associated with bone cement leakage following percutaneous kyphoplasty: a retrospective analysis.European journal of medical research · 2025Article
- Article
- Retrospective Analysis of Cement Extravasation Rates in Vertebroplasty, Kyphoplasty, and Bone Tumor Radiofrequency Ablation.Journal of clinical medicine · 2025Article
- Timing of percutaneous vertebroplasty in the management of osteoporotic vertebral compression fractures: a retrospective cohort study.Frontiers in surgery · 2025Article
- Skin Adhesive Tapes: An Effective Wound Closure Method for Percutaneous Vertebral Body Stenting.Cureus · 2024Article
- An Outline on the Advancements in Surgical Management of Osteoporosis-Associated Fractures.Cureus · 2024Review
- Construction and clinical validation of risk model for predicting bone cement leakage after the surgical management of spinal metastases.American journal of cancer research · 2024Article
- CT-guided percutaneous microwave ablation combined with bone cement injection for the treatment of transverse metastases: A case report.Open medicine (Warsaw, Poland) · 2023Article
- Evaluation of Cement Leakage and Complications After Cement-augmented Pedicle Screw Fixation: A Retrospective Case Series.In vivo (Athens, Greece)Article
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
Abstract
objectiveThe objective of this research was to investigate the risk factors of cement leakage in patients with metastatic spine tumors following percutaneous vertebroplasty (PVP).
methodsSixty-four patients with 113 vertebrae were retrospectively reviewed. Various clinical indexes, including age, sex, body mass index (BMI), smoking history, drinking history, chemotherapy history, radiotherapy history, primary cancer, location, other metastases, collapse, posterior wall defects, the laterality of injection, and the injected cement volume were analyzed as potential risk factors. Multivariate analyses were conducted to identify the independent risk factors.
resultsThe cement leakage was found 64 in 113 treated vertebrae (56.63%), in which the incidence of each type was shown as below: spinal canal leakage 18 (15.93%), intravascular leakage around the vertebrae 11 (9.73%), and intradiscal and paravertebral leakage 35 (30.97%). Tomita classification (P = 0.019) and posterior wall destruction (P = 0.001) were considered strong risk factors for predicting cement leakage in general. The multivariate logistic analysis showed that defects of the posterior wall (P = 0.001) and injected volume (P = 0.038) were independently related to the presence of spinal canal leakage. The postoperative visual analog scale (VAS) and activities of daily living (ADL) scores showed significant differences compared with the pre-operative parameters (P < 0.05). No significant differences were found in every follow-up time between the leakage group and the non-leakage group for pain management and improvement of activities in daily life.
conclusionIn our study, Tomita classification and the destruction of the posterior wall were independent risk factors for leakage in general. The defects of the posterior wall and injected volume were independently related to the presence of spinal canal leakage. The PVP procedure can be an effective way to manage the pain.
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