Evidence map›Paper›PMID 35387509›Full record

ArticleNeurorehabilitation and neural repair2022

A Novel Way of Measuring Dual-Task Interference: The Reliability and Construct Validity of the Dual-Task Effect Battery in Neurodegenerative Disease.

Jason K Longhurst, John V Rider, Jeffrey L Cummings, Samantha E John, Brach Poston, Elissa C Held Bradford, Merrill R Landers

Open access · greenAbstract read
In one paragraph

Article in Neurorehabilitation and neural repair, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
3.0field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 32 citations in OpenAlex.

  1. Trial
  2. Functional reserve mitigates cognitive-motor dual-task costs in older adults: insights from age, cohort, and behavioural strategies.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2026
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  19. A Perspective: Challenges in Dementia Research.Medicina (Kaunas, Lithuania) · 2022
    Article
  20. Dual Task Performance Is Associated with Amyloidosis in Cognitively Healthy Adults.The journal of prevention of Alzheimer's disease · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Jason K Longhurst15994Saint Louis University, St. Louis, MO, USA.ORCID 0000-0003-1853-6949
John V Rider15994Touro University Nevada, Henderson, NV, USA.
Jeffrey L Cummings14722University of Nevada, Las Vegas, NV, USA.
Samantha E John14722University of Nevada, Las Vegas, NV, USA.
Brach Poston14722University of Nevada, Las Vegas, NV, USA.
Elissa C Held Bradford15994Saint Louis University, St. Louis, MO, USA.
Merrill R Landers14722University of Nevada, Las Vegas, NV, USA.ORCID 0000-0002-4234-910X
University of Nevada, Las Vegas · USCleveland Clinic · USSaint Louis University · US

Funding

Renewal of Centers of Biomedical Research Excellence (COBRE) (Phase 2) CNTN - ResubmissionP20GM109025 · NIGMS · CLEVELAND CLINIC FOUNDATION · PI JESSICA KIRKLAND CALDWELL · 2015 to 2026
$22.8M
NIGMS NIH HHS P20 GM109025
6 · The paper itself

Abstract

backgroundDecreased automaticity is common among individuals with neurodegenerative disease and is often assessed using dual-task (DT) paradigms. However, the best methods for assessing performance changes related to DT demands remain inconclusive.

objectiveTo investigate the reliability and validity of a novel battery of DT measures (DT Effect-Battery (DTE-B)) encompassing three domains: task-specific interference, task prioritization, and automaticity.

methodsData for this retrospective cross-sectional study included 125 participants with Parkinson's disease (PD), 127 participants with Alzheimer's disease (AD), and 84 healthy older adults. Reliability analyses were conducted using a subset of each population. DTE-B measures were calculated from single and DT performance on the Timed Up and Go test and a serial subtraction task. Construct validity was evaluated via associations within the DTE-B and with theoretically supported measures as well as known-groups validity analyses.

resultsGood to excellent reliability was found for DTE-B measures of task interference (motor and cognitive DT effects) (ICCs≥.658) and automaticity (combined DT effect (cDTE)) (ICCs≥.938). Evidence for convergent validity was found with associations within the hypothesized constructs. Known-groups validity analyses revealed differences in the DTE-B among the healthy group and PD and AD groups (

conclusionsThis study provides evidence to support the DTE-B as a reliable measure of multiple constructs pertinent to DT performance. The cDTE demonstrated evidence to support its validity as a measure of automaticity. Further investigation of the utility of the DTE-B in both PD and AD, as well as other populations, is warranted.

Indexed as

Alzheimer DiseaseCadmium CompoundsNeurodegenerative DiseasesParkinson DiseaseQuantum DotsAgedCross-Sectional StudiesGaitHumansPostural BalanceReproducibility of ResultsRetrospective StudiesTelluriumTime and Motion StudiesWalkingCadmium Compoundscadmium tellurideTelluriumAlzheimer diseaseautomaticitydual-task interferencemultitasking behaviorneurobehavioral manifestationsParkinson disease

Identifiers

PMID35387509
PMCPMC9133058
OpenAlexW4226148690

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.