Evidence map›Paper›PMID 35387498›Full record

ArticleFuture medicinal chemistry2022

Repurposing dyphylline as a pan-coronavirus antiviral therapy.

Yining Wang, Sajjan Rajpoot, Pengfei Li, Marla Lavrijsen, Zhongren Ma, Nik Hirani, Uzma Saqib, Qiuwei Pan, Mirza S Baig

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Future medicinal chemistry, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Identification of broad-spectrum MJournal of enzyme inhibition and medicinal chemistry · 2025
    Article
  2. Review
  3. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 4 countries.

Yining WangDepartment of Gastroenterology & Hepatology, Erasmus MC-University Medical Center, Rotterdam, 3015 CN, The Netherlands.
Sajjan RajpootDepartment of Biosciences & Biomedical Engineering (BSBE), Indian Institute of Technology Indore (IITI), Simrol, Indore, 453552, India.ORCID 0000-0003-4126-7011
Pengfei LiDepartment of Gastroenterology & Hepatology, Erasmus MC-University Medical Center, Rotterdam, 3015 CN, The Netherlands.
Marla LavrijsenDepartment of Gastroenterology & Hepatology, Erasmus MC-University Medical Center, Rotterdam, 3015 CN, The Netherlands.
Zhongren MaBiomedical Research Center, Northwest Minzu University, Lanzhou, 730030, China.
Nik HiraniMRC Centre for Inflammation Research, Queen's Medical Research Institute, University of Edinburgh, Edinburgh, EH164TJ, UK.
Uzma SaqibDepartment of Chemistry, Indian Institute of Technology Indore (IITI), Simrol, Indore, 453552, India.
Qiuwei PanDepartment of Gastroenterology & Hepatology, Erasmus MC-University Medical Center, Rotterdam, 3015 CN, The Netherlands.
Mirza S BaigDepartment of Biosciences & Biomedical Engineering (BSBE), Indian Institute of Technology Indore (IITI), Simrol, Indore, 453552, India.ORCID 0000-0001-8292-7130
Erasmus MC · NLIndian Institute of Technology Indore · INMinzu University of China · CNQueen's Medical Centre · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

COVID-19 Drug TreatmentDyphyllineAntiviral AgentsDrug RepositioningHumansPandemicsSARS-CoV-2Antiviral AgentsDyphyllinedrug discoverydyphyllinehuman coronaviruses (HCoVs)Mprorepurposing

Identifiers

PMID35387498
PMCPMC9048854
OpenAlexW4225376118

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.