Evidence map›Paper›PMID 35387440›Full record

ArticleFrontiers in cardiovascular medicine2022

Early Change in Area Strain Detected by 3D Speckle Tracking Is Associated With Subsequent Cardiotoxicity in Patients Treated With Low Doses of Anthracyclines.

Rafael B Piveta, Ana Clara T Rodrigues, Marcelo L C Vieira, Cláudio H Fischer, Tania R Afonso, Edgar Daminello, Felipe M Cruz, Tatiana F G Galvão, Edgar B L Filho, Marcelo Katz and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Review
  9. Review
  10. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 2 institutions in 1 country.

Rafael B PivetaDepartment of Echocardiography, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Ana Clara T RodriguesDepartment of Echocardiography, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Marcelo L C VieiraDepartment of Echocardiography, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Cláudio H FischerDepartment of Echocardiography, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Tania R AfonsoDepartment of Echocardiography, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Edgar DaminelloDepartment of Echocardiography, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Felipe M CruzDepartment of Chemotherapy, Instituto Brasileiro de Controle do Câncer, São Paulo, Brazil.
Tatiana F G GalvãoDepartment of Echocardiography, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Edgar B L FilhoDepartment of Echocardiography, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Marcelo KatzDepartment of Echocardiography, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Samira S MorhyDepartment of Echocardiography, Hospital Israelita Albert Einstein, São Paulo, Brazil.
Hospital Israelita Albert Einstein · BRInstituto Brasileiro de Controle do Câncer · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the prognostic impact of the parameters of myocardial deformation using three-dimensional speckle tracking echocardiography (3DSTE) in patients with breast cancer who underwent chemotherapy with low doses of anthracyclines. Background: Chemotherapy-related cardiotoxicity has an important prognostic impact on cancer survivors. Three-dimensional STE has revealed more consistent data than two-dimensional techniques and may represent a more accurate tool in the evaluation of myocardial function in patients who underwent chemotherapy. Methods: We evaluated patients with breast cancer who were treated with anthracyclines (associated or not with trastuzumab) in five stages: baseline, after cumulative doses of 120 and 240 mg/m Results: We evaluated 51 female patients who were aged 50.6 ± 11 years. After the cumulative dose of 240 mg/m Conclusion: In patients with breast cancer, 3DSTE detected early changes in area strain after very low doses of doxorubicin. The 3DGAS early changed to abnormal values was associated with a subsequent decrease in LVEF, representing a promising technique to predict chemotherapy-induced cardiomyopathy.

Indexed as

3D speckle tracking3D straincardiotoxicitychemotherapyechocardiography

Identifiers

PMID35387440
PMCPMC8979028
OpenAlexW4221045813

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.