ArticleFrontiers in cardiovascular medicine2022
Diagnostic Accuracy of Subtraction Coronary CT Angiography in Severely Calcified Segments: Comparison Between Readers With Different Levels of Experience.
Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.
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Who cites it
6 citing papers in PubMed, 4 citations in OpenAlex.
- U-shaped relationship between coronary artery calcification and underestimation of moderate coronary stenosis by coronary computed tomography angiography.Cardiovascular diagnosis and therapy · 2026Article
- Age- and Sex-Related Patterns in Coronary CT Angiography Referrals and Coronary Atherosclerotic Burden: A Single-Center Real-World Referral-Based Analysis.Medicina (Kaunas, Lithuania) · 2026Article
- Optimizing carotid plaque visualization: the advantage of subtraction imaging from dual-layer spectral CT.BMC medical imaging · 2026Article
- Subtraction fractional flow reserve with computed tomography and pericoronary fat attenuation index enhances the identification of revascularization needs in patients.BMC medical imaging · 2025Article
- Accuracy and consistency of subtraction dual-layer spectral computed tomography in diagnosing coronary stenosis: invasive coronary angiography validation study.Quantitative imaging in medicine and surgery · 2025Article
- [Assessment of Coronary Stenosis Using Coronary CT Angiography in Patients with High Calcium Scores: Current Limitations and Future Perspectives].Journal of the Korean Society of Radiology · 2024Review
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Authors and funding
9 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Purpose: Subtraction coronary CT angiography (CCTA) may reduce blooming and beam-hardening artifacts. This study aimed to assess its value in improving the diagnostic accuracy of readers with different experience levels. Method: We prospectively enrolled patients with target segment who underwent CCTA and invasive coronary angiography (ICA). Target segment images were independently evaluated by three groups of radiologists with different experience levels with CCTA using ICA as the standard reference. Diagnostic accuracy was measured by the area under the curve (AUC), using ≥50% stenosis as the cut-off value. Results: In total, 134 target segments with severe calcification from 47 patients were analyzed. The mean specificity of conventional CCTA for each group ranged from 22.4 to 42.2%, which significantly improved with subtraction CCTA, ranging from 81.3 to 85.7% (all Conclusion: Subtraction CCTA could improve the diagnostic accuracy of radiologists at all experience levels of CCTA interpretation.
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