Evidence map›Paper›PMID 35387431›Full record

ArticleFrontiers in cardiovascular medicine2022

Energy Drinks: Effects on Blood Pressure and Heart Rate in Children and Teenagers. A Randomized Trial.

Felix Sebastian Oberhoffer, Pengzhu Li, André Jakob, Robert Dalla-Pozza, Nikolaus Alexander Haas, Guido Mandilaras

Abstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it.

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  11. Pediatric Exposures Associated with Caffeine Energy Products Reported to United States Poison Centers, 2011-2023.Journal of medical toxicology : official journal of the American College of Medical Toxicology · 2025
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  12. Regulatory Efforts and Health Implications of Energy Drink Consumption by Minors in Poland.Medical science monitor : international medical journal of experimental and clinical research · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Felix Sebastian OberhofferDivision of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
Pengzhu LiDivision of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
André JakobDivision of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
Robert Dalla-PozzaDivision of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
Nikolaus Alexander HaasDivision of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.
Guido MandilarasDivision of Pediatric Cardiology and Intensive Care, University Hospital, LMU Munich, Munich, Germany.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: The consumption of Energy Drinks (ED) is very popular among children and teenagers. While potential cardiovascular side effects of these beverages are suggested, the acute impact of ED consumption on the pediatric cardiovascular system has not been systematically examined yet. The aim of this study was to investigate the acute effects of ED consumption on blood pressure and heart rate in healthy children and teenagers. Methods: This study was a randomized, single-blind, placebo-controlled, crossover clinical trial. On two consecutive days, the study participants were asked to consume a weight-adjusted amount of an ED (3 mg caffeine per kg of body weight) or a placebo containing a similar amount of sugar but without conventional ED ingredients. Systolic blood pressure (SBP), diastolic blood pressure (DBP) and heart rate were measured at the following time points: baseline as well as 30, 60, 120 and 240 min after beverage consumption. Results: In total, 27 healthy children and adolescents (mean age 14.53 ± 2.40 years, 14 male) were included in the present study. Compared to placebo intake, mean SBP was demonstrated to be up to 5.23 mmHg ( Conclusions: The acute ED consumption is associated with a significantly increased SBP and DBP in healthy children and teenagers. Minors, particularly those with pre-existing health conditions, should be discouraged from drinking EDs. Clinical Trial Registration: https://www.drks.de/drks_web/, identifier: DRKS00027580.

Indexed as

blood pressureEnergy Drinksheart ratepediatricsprevention

Identifiers

PMID35387431
PMCPMC8978997

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.