Evidence map›Paper›PMID 35387233›Full record

ArticleSynthetic and systems biotechnology2022

Comparative functional genomics identifies an iron-limited bottleneck in a

Francesca V Gambacorta, Ellen R Wagner, Tyler B Jacobson, Mary Tremaine, Laura K Muehlbauer, Mick A McGee, Justin J Baerwald, Russell L Wrobel, John F Wolters, Mike Place and 13 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Synthetic and systems biotechnology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Development ofBiotechnology reports (Amsterdam, Netherlands) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. Advances inJournal of fungi (Basel, Switzerland) · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

23 authors at 1 institution in 1 country.

Francesca V GambacortaDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Ellen R WagnerDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Tyler B JacobsonDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Mary TremaineDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Laura K MuehlbauerDepartment of Chemistry, University of Wisconsin-Madison, Madison, WI, USA.
Mick A McGeeDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Justin J BaerwaldDepartment of Chemical and Biological Engineering, University of Wisconsin-Madison, Madison, WI, USA.
Russell L WrobelDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
John F WoltersDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Mike PlaceDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Joshua J DietrichDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Dan XieDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Jose SerateDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Shabda GajbhiyeDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Lisa LiuDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Maikayeng Vang-SmithDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Joshua J CoonDepartment of Chemistry, University of Wisconsin-Madison, Madison, WI, USA.
Yaoping ZhangDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Audrey P GaschDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Daniel Amador-NoguezDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Chris Todd HittingerDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Trey K SatoDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
Brian F PflegerDOE Great Lakes Bioenergy Research Center, University of Wisconsin-Madison, Madison, WI, USA.
University of Wisconsin–Madison · US

Funding

Institutional Training in the Genomic SciencesT32HG002760 · NHGRI · UNIVERSITY OF WISCONSIN-MADISON · PI Qiongshi Lu · 2003 to 2026
$17.7M
Biotechnology Training ProgramT32GM135066 · NIGMS · UNIVERSITY OF WISCONSIN-MADISON · PI SCOTT M. COYLE, BRIAN G FOX · 2020 to 2026
$7.0M
NHGRI NIH HHS T32 HG002760NIGMS NIH HHS T32 GM135066
6 · The paper itself

Abstract

Metabolic engineering strategies have been successfully implemented to improve the production of isobutanol, a next-generation biofuel, in

Indexed as

Fe incorporationFunctional genomics analysisIsobutanolPathway localizationSaccharomyces cerevisiae

Identifiers

PMID35387233
PMCPMC8938195
OpenAlexW4220844838

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.