Evidence map›Paper›PMID 35387224›Full record

ArticleComputational and mathematical methods in medicine2022

Effect of Sirtuin-1 and Wnt/

Kunming Zhu, Weiwei Xu, Donghe Han, Xifan Mei

RetractedOpen access · hybridAbstract readRetracted Publication
PubMed Full text at PMC Publisher
In one paragraph

Article in Computational and mathematical methods in medicine, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.8field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 6 citations in OpenAlex.

  1. miR-24-3p promotes spinal cord injury repair in rats by inhibiting ferroptosisNan fang yi ke da xue xue bao = Journal of Southern Medical University · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Retracted: Effect of Sirtuin-1 and Wnt/Computational and mathematical methods in medicine · 2023
    Article
  6. The sirtuin family in health and disease.Signal transduction and targeted therapy · 2022
    Review
4 · The record

Corrections and comments

  • Retraction · 2023-06-28Concerns/Issues about Data · Concerns/Issues about Human Subject Welfare · Concerns/Issues about Referencing/Attributions · Concerns/Issues about Peer Review · Investigation by Journal/Publisher · Investigation by Third Party · Lack of IRB/IACUC Approval and/or Compliance · Unreliable Results and/or Conclusions ·
  • Retracted
5 · Who and what money

Authors and funding

4 authors at 2 institutions in 1 country.

Kunming ZhuDepartment of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China.
Weiwei XuZoucheng People's Hospital, Shandong Province, China.
Donghe HanDepartment of Neurobiology, Jinzhou Medical University, Jinzhou, Liaoning, China.
Xifan MeiDepartment of Orthopedics, The First Affiliated Hospital of Jinzhou Medical University, Jinzhou, Liaoning, China.ORCID https://orcid.org/0000-0002-4452-8005
Jinzhou Medical University · CNZoucheng People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sirtuin-1 (SIRT1) has anti-inflammatory and antioxidant effects and has been reported to be involved in spinal cord injury (SCI). Wnt/

Indexed as

Sirtuin 1Spinal Cord InjuriesAnimalsApoptosisbeta CateninForkhead Transcription FactorsHydrogen PeroxideRatsRats, Sprague-DawleyWnt Signaling Pathwaybeta CateninForkhead Transcription FactorsFOXO4 protein, ratHydrogen PeroxideSirt1 protein, ratSirtuin 1

Identifiers

PMID35387224
PMCPMC8977327
OpenAlexW4220992971

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.