Evidence map›Paper›PMID 35386836›Full record

ArticleEvolution letters2022

Population-level variation in parasite resistance due to differences in immune initiation and rate of response.

Amanda K Hund, Lauren E Fuess, Mariah L Kenney, Meghan F Maciejewski, Joseph M Marini, Kum Chuan Shim, Daniel I Bolnick

Open access · goldAbstract read
In one paragraph

Article in Evolution letters, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
4.4field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 27 citations in OpenAlex.

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  13. Destabilized host-parasite dynamics in newly founded populations.bioRxiv : the preprint server for biology · 2024
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Amanda K HundDepartment of Ecology, Evolution, and Behavior University of Minnesota St. Paul Minnesota 55123.ORCID https://orcid.org/0000-0001-7758-6757
Lauren E FuessDepartment of Ecology and Evolutionary Biology University of Connecticut Storrs Connecticut 06269.ORCID https://orcid.org/0000-0003-0197-7326
Mariah L KenneyDepartment of Ecology and Evolutionary Biology University of Connecticut Storrs Connecticut 06269.ORCID https://orcid.org/0000-0003-4884-108X
Meghan F MaciejewskiDepartment of Ecology and Evolutionary Biology University of Connecticut Storrs Connecticut 06269.ORCID https://orcid.org/0000-0002-2770-787X
Joseph M MariniDepartment of Ecology and Evolutionary Biology University of Connecticut Storrs Connecticut 06269.
Kum Chuan ShimDepartment of Ecology, Evolution, and Behavior University of Texas at Austin Austin Texas 78712.
Daniel I BolnickDepartment of Ecology and Evolutionary Biology University of Connecticut Storrs Connecticut 06269.ORCID https://orcid.org/0000-0003-3148-6296
University of Connecticut · USTexas State University · USThe University of Texas at Austin · USUniversity of Minnesota · US

Funding

Reciprocal genetics of recently-evolved vertebrate immunity and peritoneal helminth counter-adaptationR01AI123659 · NIAID · UNIVERSITY OF TEXAS AT AUSTIN · PI Daniel Imara Bolnick · 2017 to 2026
$3.8M
NIAID NIH HHS R01 AI123659
6 · The paper itself

Abstract

Closely related populations often differ in resistance to a given parasite, as measured by infection success or failure. Yet, the immunological mechanisms of these evolved differences are rarely specified. Does resistance evolve via changes to the host's ability to recognize that an infection exists, actuate an effective immune response, or attenuate that response? We tested whether each of these phases of the host response contributed to threespine sticklebacks' recently evolved resistance to their tapeworm

Indexed as

Fibrosisimmune evolutionimmune responseparasite resistanceSchistocephalus solidusthreespine stickleback

Identifiers

PMID35386836
PMCPMC8966477
OpenAlexW4213447238

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.